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Joint Disorders Causes and Risk Factors

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fuckdaveliu's version from 2018-05-18 22:47

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Question Answer
Degenerative Joint Disease (Osteoarthritis)Degeneration of the articulate cartilage, due to wear and tear. Major Riks Factors include Age, Obesity, Trauma, Sex(female)
Rheumatoid Arthritis Chronic Systemic Immune disease, classically in wowen of late childbearing age, associated with HLA-DR4
Ankylosing SpondylarthritisJoint Disorder associated with HLA-B27, arises in young adults, mostly males
Reiter SyndromeArises in young adults usually males weeks after GI, or Chlamydia trachomatis infection
Psoriatic ArthritisSeen in 10% of cases of Psoriasis
Infectious ArthritisArthritis due to an infectious agent, N. gonorrhoeae in young adults, S.Aureus in older children and adults
Primary Gout Due to hyperuricemia, due to overproduction or decrease excretion of uric acid. (uric acid is derived from purines metabolism and is excreted by the kidney). The Uric acid builds up leading to monosodium urate (MSU) crystals being deposited especially in the joints
Secondary GoutLeukemia and myeloproliferative disorders, Lesch-Nyhan Syndrome, Renal Insufficiency
Acute Gout Alcohol or consumption of meat may precipitate arthritis
Chronic GoutLong standing Uric Acid
Pseudo GoutDeposition of Calcium pyrophosphate
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