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IPDM WK 7 Osteoarthritis Part 1

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alchemist04's version from 2016-06-07 04:13

Section

Question Answer
What are the common signs of Osteoarthritis? (1)(1) Joint stiffness for approx. 30 mins upon waking up and resolve with motion while RA does not resolve and takes month (~ 6mo). any stiffness lasting more than 6 wks is RA
What are the common signs of Osteoarthritis? (2)(2) Inflammatory synovitis
What are the common signs of Osteoarthritis? (3)(3) Warm, red and tender joint
What are the common signs of Osteoarthritis? (4)(4) Osteophytes (Bony enlargements)
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Question Answer
What are the common signs of Osteoarthritis? (5)(5) Limited motion
What are the common signs of Osteoarthritis? (6)(6) Weakness or instability especially at for knee Osteophytes
What are the common signs of Osteoarthritis? (7)(7) Age onset is usually after 50 yrs while that of RA is in juvenile or adult of 35 - 50 yo
What are the common signs of Osteoarthritis? (8)(8) Speed of onset is Slow, while that of RA is Rapid
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Question Answer
True or false? Joint symptoms of OA is Pain, swelling, warmth and stiffnessFalse, it is Pain, bony enlargement (osteophytes)
True or false There is no presence or mild and localized inflammation in OATrue, it could be w/o inflammation or with mild, local inflammation
True or false? ESR is normal in OATrue. Elevated ESR is only in RA
True or false? there is NO systemic manifestations of OA?True
True or False? Joint patter of both OA and RA could be symmetric or asymmetric?False. OA could be either symmetric or asymmetric while RA is only symmetric
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Question Answer
What are the risk factors of OA?(1) Age, (2) Obesity (3) previous joint injury (4) Repetitive use of joints (5) Gender - females more affected
What is the 1st line of treatment to consider for OA treatment?APAP
What is the 1st topical treatment to consider before systemic pharm treatment?NSAIDs
What is the last line of treatment to recommended for OA?Opioids
True or false? Intraarticular therapies and Opioids are NOT recommemded for hand OA?True
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Question Answer
What are the non-Pharm treatment options of Osteoarthritis (1) [Exact Quiz Question, EQQ](1) Joint protection techniques
What are the non-pharm treatment options of Osteoarthritis (2) [EQQ](2) Assistive device for ADL e.g walker, sphincter, cane
What are the non-Pharm treatment options of Osteoarthritis (3) [EQQ](3) Thermal agent to alleviate pain and stiffness
What are the non-Pharm treatment options of Osteoarthritis (4)(4) Exercises
What are the non-Pharm treatment options of Osteoarthritis (5)(5) Weight loss for over weight
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Question Answer
What are the Pharmacological treatment for OA? (1)(1) APAP (2) NSAIDs (5) Celecoxib/Celebrex (6) Topical Caosaicin/Zostrix
What are the Pharmacological treatment for OA? (2)(1) Diclofenac topical solution/ Pennsaid (2) Diclofenac gel/Voltaren
What are the Pharmacological treatment for OA? (3)(1) Glucosamine/Chondroitin
What are the Pharmacological treatment for OA? (4)(1) Tramadol (Ultram, Ultracet) (2) Opioids (3) Lidocaine (Lidoderm) Patch
What are the Pharmacological treatment for OA? (5)(1) Intraarticular Corticosteroid injections (2) Anthroplasty
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Question Answer
What are the choosing treatment options for OA pt with the Risk of GI Ulcer and Bleeding?(1) Celecoxib + PPI or Misoprostol (2) Nonselective NSAID + PPI or misoprostol
What are the choosing treatment options for OA pt with the Risk of CV or risk of GI?Naproxen + PPI/misoprostol or Tramadol
What is the choosing treatment option for OA pt with the Risk of Chronic Kidney disease (CDK)?Tramadol or Intraarticular injections
What is the choosing treatment option for OA with the Risk of Sub therapeutic response to NSAIDs or Celecoxib?Tramadol
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Question Answer
MOA of APAP?Central acting Analgesic w/ minimal anti-inflammation properties
What is APAP usual dose(1) 325 - 650 mg Q4-6h (2) 1000 mg Q6-8h
What is the FDA maximum dose for APAP?4000mg or 4g QD (per day)
What is the BBW of APAP?Hepatotoxicity
What are the contraindications of APAP?(1) Hepatic impairment (2) severe active liver disease
What are the adverse effects APAP?N/V, Hypersensitivity reaction or skin reaction (SJS/TEN)
What are the counseling points of APA?(1) do not take more than 1g per dose (2) Avoid drinking alcohol
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Question Answer
MOA of NSAIDS?(1) Inhibits COX 1 and 2, (2) inhibits Prostaglandin synthesis (3) has analgesic, antipyretic and anti-inflammatory properties
Common OTC NSAIDs(1) Ibuprofen (2) Naproxen
What is BBW for NSAIDs?Increase risk of (1) CV like MI and Stroke (2) GI bleeding (3) GI Ulcer (3) GI perforation (No Renal Impairment * Exactly quiz question)
What is the contraindication of NSAIDs?CABG surgery
What are the adverse effects of NSAIDs?(1) Edema/fluid retention, heartburn, nausea, abdominal pain, renal impairment
What are the cautions for NSAIDs?(1) patient w/ renal dysfunction, CV, history of GI bleeding
What are counseling points for NSAIDs?(1) Take w/ food (2) Avoid drinking alcohol
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