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IPDM I WK 6 UI Antimuscarinics Agents for UUI and OAB

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alchemist04's version from 2016-05-14 14:27

Section

Question Answer
counseling points for Ditropan Patient? (1)can cause dry mouth
counseling points for Ditropan Patient? (2)avoid mouth watches with alcohol
counseling points for Ditropan Patient? (3)sip on water, use artificial saliva, suck on ice chips or sugar free candy
counseling points for Ditropan Patient? (4)can cause constipation
counseling points for Ditropan Patient? (5)dry water adequately and eat dietary fiber intake
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Question Answer
counseling points for Ditropan Patient? (6)use stool softener or a laxative
counseling points for Ditropan Patient? (7)may cause drowsiness
counseling points for Ditropan Patient? (8)alcohol may make drowsiness worse
counseling points for Ditropan Patient? (9)do not operate or drive dangerous machinery
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Question Answer
counseling points for Gelnique patients? (1)Apply at shoulder and arm, stomach or tights
counseling points for Gelnique patients? (2)Apply to different site each DAY
counseling points for Gelnique patients? (3)Apply to clean, dry, intact skin on the abdomen, shoulder or thighs
counseling points for Gelnique patients? (4)Apply 3 pumps (84 mg) topically once daily
counseling points for Gelnique patients? (5)Do not bath, swim, or shower for 1 hr after application
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Question Answer
counseling point for Oxytrol (1)cause less dry mouth
counseling point for Oxytrol (2)OTC patch shd be applied every 4 days
counseling point for Oxytrol (3)Rx patch shd be applied every 3-4 days
counseling point for Oxytrol (4)Remove prior to a MRI procedure
counseling point for Oxytrol (5)Water will not change the way it works
counseling point for Oxytrol (6)apply at clean, dry, intact skin on the abdomen, hips or buttocks
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Question Answer
Example of Beta-3 Adrenergic Receptor AgonistMirabegron
Brand name for MirabegronMyrbetriq
Indication for MyrbetriqOAB W/ symptoms of urge urinary incontinence, and urinary frequency
MOA of MirabegronIncreases bladder capacity by relaxing the detrusor muscle during storage phase
Dosing of Myrbetriqtake 25 mg PO once daily, increase to 50 mg PO once daily after 8 weeks.
Dose adjustment for Mirabegron(1) adjust for both hepatic and renal (2) avoid in severe hepatic impairment or ESRD
Contraindication for Myrbetriqsevere HTN (>/=180/110 mmHg)
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Question Answer
What are the side effects of Mirabegron? (1)HTN
What are the side effects of Mirabegron? (2)UTI
What are the side effects of Mirabegron? (3)Nasopharyngitis
How does Myrbetriq affects CYP2d6?It is a MODERATE CYP2D6 inhibitor
As a moderate CYP2D6 inhibitor, what would be the effect on drug like digoxin, how do you adjust dose?The effect will be an accumulation of drug in the body blood with less metabolism. Initiate the lowest amount of digoxin dose.
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