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IP 3 Immunology Nomenclature of Immune System Cells

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alchemist04's version from 2018-12-28 00:40

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Two lineage of Pluripotent hematopoietic stem cells areMyeloid and Lymphoid
Myeloid gives rise toNeutrophils, Eosinophils, basophils, monocytes, erythrocytes and platelets
Lymphoid gives rise toT and B cells, Natural killer (NK) cells/lymphocytes
Leukocytes or white blood cells consist ofNeutrophils, Eosinophils, basophils, monocytes, T and B cells, Natural killer (NK) cells/lymphocytes (i.e. Myeloid (minus Erythrocytes and platelet) and Lymphoid
Granulocytes areNeutrophil, Eosinophil, Basophil
Mononuclear cells areMonocyte, T Cell, B Cell, NK cells
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Polymorphs are granulocytes which areNeutrophil, Eosinophil, Basophil
Lymphocytes areT cells, B cells and NK cells (minus Monocytes)
Phagocytes areNeutrophil, Monocyte
Which immune cells are found in the tissues?Tissue eosinophil, Mast cells, Macrophage (histiocyte), T lymphocyte, Plasma cell, NK
Which Leukocytes mature w/n the red bone marrow?Neutrophils, Eosinophils, basophils, monocytes, B lymphocytes, thymocytes
important properties of the adaptive immune response include (a) Specificity and diversity (b)memory (c) clonal expansion (d) Non-reactivity to self
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What are the 2 types of Adaptive immunity?(a) Humoral Immunity (b) Cell-mediated immunity
The part of the antigen that is recognized by the immune system is calledthe antigenic epitope, or determinant
What is the difference btw MHC and HLA?MHC are group of cell presenting glycoproteins found on the surface of a cell while HLA are the group of cell presenting glycoprotein found on humans. MHC and HLA are used interchangeably.
What is the fx of MHC/HLA?it displays a protein fragment , or peptide, on the cell surface to either be recognized (if foreign) or ignored (if self) by immune cells
Name all APCs (Antigen-presenting cells) in a Class II MHC/HLA; aka "professional antigen-presenting cells"(1) Monocytes/Macrophages (2) Dendritic cells (3) B-cells
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CD 4 Cells are?Helper T lymphocytes
CD 8 Cells are?Cytotoxic T lymphocytes
Explain the MHC Class I pathway MHC I found on the surface of all cell membrane picks microbe (phagocytes from the surface into the cytosol) from the cell cytoplasm (Intracellularly) > antigen is presented to Cytotoxic T cell (CD 8 cells) > antigen is killed and fragments/residues are removed from the cell
Explain the MCH Class II pathwayMCH II picks antigens extracellularly from APCs > antigen is presented to Helper T cell (CD 4 cells) > Antigen + helper T cell activate and recruit other immune cells
What is clonal selection?A process in which the B cell grows and multiply after engulfing/phagocytes, via cloning, into army of B cells with the same properties and characteristics (antigen-specific receptors)
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