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Ion channels

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imissyou419's version from 2016-10-16 00:00

Section

Question Answer
common cations in our bodyNa+, K+, Ca+, Mg2+
common anions in our bodyCl-, HCO3-
electrical sensor for gatingVG ion channels - most Na+ channels, L- and T-type Ca+ channels
chemical sensor for gatingnAChR, AMPAR, NMDAR, GABAR
mechanical sensor for gatingmechanically gated ion channels
K+ vs Na+ hydration and motilityK+ has lower hydration number thus high motility, Na+ has higher hydration number thus low motility
Hydration number depends oncharge density (higher charge, lower ion size = higher charger density)
memorize

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