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Integument pharmacology

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sidsterr's version from 2017-11-25 06:08

Section

Question Answer
provitamin A cartenoidsalpha-carotene, beta-carotene, beta-cryptoxanthin
non-provitamin A cartenoidslutein, zeaxanthin, lycopene
retinoid 1st genretinol, tretinoin, isotretinoin, alitretinoin
retinoid 2nd genetretinate, acitretin
retinoid 3rd genadapalene (differin), tazarotene (tazorac), bexarotene
non-retinoid acne salicylic acid, propylene glycol, benzoyl peroxide
glucocorticoid hormonescortisol, cortisone, corticosterone
3 layers of cortical cellsglomerulosa (mineralocorticoids); fasciculata (glucocorticoids); reticularis (gonadocorticoids)
TNF alpha inhibitors for psoriasisetanercept (enbrel), infliximab (remicade), adalimumab (humira)
IL-17A antagonists for psoriasissecukinumab (cosentyx) IgG1; ixekizumab (taltz) IgG4
IL-12/IL-23 antagonists for psoriasisustekinumab (stelara)
topical corticosteroid- class 1very potent; clobetasol propionate (dermovate)
topical corticosteroid- class 7weakest class, poor lipid permeability; hydrocortisone (hytone)
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