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Immunology FA, MHC I and II

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krinpa's version from 2015-05-25 19:05

Section 1

Question Answer
MHC I lociHLA-A, HLA-B, HLA-C
MHC II lociHLA-D, HLA-DP, HLADQ
binding MHC ITCR and CD8
binding MHC IITCR and CD4
Expression of MHC Iexpressed on all nucleated cells not expressed on RBCs
Expression of MHC IIexpressed only on APC
Function of MHC I present endogenously synthesized antigens to CD8+ cytotoxic T cells
Function of MHC IIpresent exogenously synthesized protein (bacterial, viral capsid) to T-helper cells
antigen loading MHCIantigen peptides loaded onto complex in RER after delivery via TAP peptide Transporter
antigen loading MHC II antigen loaded following release of invariant chain in acidified endosome
MHC I mode of transport to cell surfaceB2-microglobulin
memorize

Section 2