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Immunity 2

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juniperk's version from 2018-03-21 03:20

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Question Answer
How long does chronic inflammation last?longer than 2 weeks
What is the difference between B & T cells?B-Cells produce antibodies that react with antigen (humoral immunity) T-Cells attack the antigen directly.
What are the 2 ways Tc cells fight antigens?Membrane is destroyed or the Tc cells will release a cytotoxic substance that will destroy the cells
How does T helper cells control the immune response?Releases cytokines which are produced by many cell types in response to microbial or physical tissue damage. Cytokines have effects on WBC production and response to damage. Increase WBC production in bone marrow.
What does TH1 Cells stimulate? TH2?TH1 stimulate T cytotoxic cells (killer cells). TH2 stimulate the B lymphocytes.
Where are B cells made? T cells?B cells are made in the bone marrow. T cells are made in the thymus.
What are IgM? IgG?IgMs are the first responders and circulate the bodily fluids. IgG are the second responders and also circulate in fluids.
What are IgA? where are they found?Found in secretions amoung mucus membrane like tears or saliva or lactating mother's milk. Goal: to protect from antigen getting into the body.
IgD? found where?Found on the surface of many B cells. Acts as receptors.In B cells, IgD's function is to signal the B cells to be activated.
IgE? Found where?Found on the mast cells. Tries to prevent mast cells from breaking down. These antibodies travel to cells that release chemicals, causing an allergic reaction.
What is the difference between MCH1 and MCH2?MCH1 tells the Tc (cytotoxic cells) to kill. MCH2 tells the T helper cell to start the immune response (humoral immunity)
How does macrophages communicate with T cells?Presents antigens to Tcells
What is the primary immune response (4 steps)? How long can this take?1 Macrophages must eat the antigen, then present it to TH cells. 2. TH cells must activate B cells 3. B cells produce antibodies 4. Then plasma antibody levels rise. This can take 2-3 weeks.
What is the secondary immune response? (2 steps) 1. B memory cells respond to the antigen immediately. 2. Plasma antibody levels rise within days. This is the reason we need a booster shot. IgG is the second responder and can cross the placental barrier.
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