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munsele's version from 2016-07-06 14:09

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Question Answer
SolodynMinocycline
TMP component per tablet of Bactrim DS160mg
Bactrim IV to PO1:1
Beta lactams have what type of killingtime dependent
CefuroximeCeftin
Oritavancin and dalbavancinLipopeptides with activity against Staphylococci (MSSA and MRSA) and Streptococci
Oritavancin and dalbavancin dosing Oritavancin is a one-time dose and dalbavancin is given as two doses (one week apart)
LinezolidZyvox
Linezolid classoxazolidinone
Zyvox SEbone marrow suppression
Ratio of sulfamethoxazole to trimethoprim5:1
Macrobid toxicityPulomary
Macrobid admintake with food to enhance absorption
Extended infusion Zosyn optimizes which dosing strategy Time above MIC
Which abx class effects blood sugar Quinolones
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Question Answer
Options to treat VRECubicin, Tygvacil, Sivextro
MoxatagAmoxicillin
Moxatag adminwithin 1h of a meal
DoribaxDoripenem
Cubicin and Doribax dose adjin renal impairment
Abx associated with szPCN, B lactams, Cipro, Ganciclovir, Imipenem
DOC for primary peritonitisRocephin
Caution with which ceph if alcohol abuseCefotetan (disulfiram rxn)
Class examples that exhibit concentration dependent killingQuinolones, aminoglycosides, daptomycin
Agents not assoc with prolonging QTB lactams, PCN
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Question Answer
Length of peri-operative abx therapy for surgeries24h or less
Invanzertapenem
Common pathogens for CAPmycoplasma, h flu, strep pneumo
CDI first lineFlagyl 500mg TID for 10-14 days
Treatments for latent TBRifampin, Isoniazid
Preferred drug regimen for TBrifampin, isoniazid, pyrazinamide, ethambutol
If recurrence of CDI with same severity regimen used should besame as first regimen
DOC for ESBL infxnscarbapenems
Outpt CAP txmacrolide or doxy
Outpt CAP tx with comorbidities such as heart, lung, liver, renal disease, or DM immunosuppression, abx use within last 3 mo, aslpenia, alcoholism, malignanciesb lactam with macrolide, resp quinolone
Pyrazinamide SEhepatotoxicity, DNU in gout patients
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Question Answer
Ketektelithromycin
Risk factors for FQ tendonitisage, steroid use, transplant hx
Daptomycin for pneumoniaNO! degraded by lung surfactant
Ethambutol serious SEoptic neuritis
Rocky mountain spotted fever txdoxy or tetracycline
Gonorrhea txrocephin and zith - don't use monotherapy d/t resistance issues
Tularemia txgent or tobra
Traveler's diarrhea prophylaxisBismuth subsalicylate
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Question Answer
First line CMV txvalgancyclovir
Toxo first line txSulfadiazine + pyrimethamine + leucovorin
CD4 level to initiate proph for PCP<200
CD4 level to initiate proph for Toxo<100
MAC prophyZith 1200mg weekly
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