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Hypersensitivity quiz

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laurelmoon718's version from 2015-11-21 23:59

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Question Answer
what type of hypersensitivity: anaphylaxis (bee sting, some food/drug allergies)type I
what type of hypersensitivity: allergic and atopic disorders (rhinitis, hay fever, eczema, hives, asthma)type I
what is the presentation of type I hypersensitivity disorders- immediate, anaphylactic, atopic
what is associated with type I hypersensitivity disorders- IgE binds mast cells and basophils, re-exposure IgE crosslink, mast cells release mediators, TH2
what is the presentation of type II hypersensitivity disorders - disease tends to be specific to tissue or bind to Ag on surface of circulating, IgG, IgM
what is the presentation of type III hypersensitivity disorders- can be associated with vasculitis and systemic manifestations
what is associated with type III hypersensitivity disorders- immune complex activates complement eventually leading neutrophils to release lysosomal enzymes
what is the presentation of type IV hypersensitivity disorders- responses is delayed and does not involved antibodies (vs type I, II, and III)
what type of hypersensitivity: wheal and flaretype I
what type of hypersensitivity: allergic rhinitis, conjunctivitis (upper resp), asthma (lower resp)type I
what type of hypersensitivity: urticaria, angioedema, anaphylaxis type I
what type of hypersensitivity: late phase reaction 2-24 hrs later type I (cytokines: IL3, IL5, GM-CSF (eosinophils), TNF, IL1 (adhesion, influx)
what type of hypersensitivity: hemolytic anemiatype II (opsonization, phagocytosis)
what type of hypersensitivity: erythroblastosis fetalistype II (opsonization, phagocytosis)
what type of hypersensitivity: acute hemolytic transfusion reactionstype II (opsonization, phagocytosis)
what type of hypersensitivity: rheumatic fevertype II
what type of hypersensitivity: Goodpasture's syndrometype II (complement, Fc-Receptor leads to inflammation, neutrophils and ROS)
what type of hypersensitivity: Graves' diseasetype II (antibody mediated cellular dysfunction)
what type of hypersensitivity: myasthenia gravistype II (antibody mediated cellular dysfunction)
what type of hypersensitivity: SLEtype III
what type of hypersensitivity: rheumatoid arthritistype III
what type of hypersensitivity: polyarteritis nodosumtype III
what type of hypersensitivity: poststreptococcal glomerulonephritis type III
what type of hypersensitivity: serum sicknesstype III
what type of hypersensitivity: arthus reaction (swelling and inflammation following tetanus vaccine)type III
what type of hypersensitivity: type 1 DMtype IV (cell mediated cytotoxicity)
what type of hypersensitivity: multiple sclerosistype IV (delayed)
what type of hypersensitivity: Guillain-Barre syndrometype IV (delayed)
what type of hypersensitivity: Hashimoto's thyroiditistype IV
what type of hypersensitivity: Graft-versus-host diseasetype IV (cell mediated cytotoxicity)
what type of hypersensitivity: PPD (test for M. tuberculosis)type IV (delayed)
what type of hypersensitivity: viral hepatitis (HepB)type IV (cell mediated cytotoxicity)
what type of hypersensitivity: contact dermatitis (poison ivy, nickel allergy)type IV (delayed)
memorize

 

Question Answer
antinuclear antibodies (ANA)SLE, nonspecific
anti-dsDNA, anti-SmithSLE
low C3, C4 levels, consumptionSLE
inject Ag leads to vasculitis after 4-10 hrsArthus
anti-IgG *rheumatoid factor, - rheumatoid arthritis
memorize