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Hyperlipidemia

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vagecahu's version from 2015-11-09 17:17

Section 1

Question Answer
Statinslower LDL 18-55, non HDL -15-51, HDL increase 5-15, TG - 7-30
niacin LDL - 5-25, non HDL - 8-23, HDL +15-35, TG- 20-50
Fibric acid LDL -5 to +20, HDL +10-20, non HDL -5-19, TG -20-50
Bile acid sequestrantsLDL -15-30, non HDL -4-16, HDL +3-5, TG + 0-10
Omega 3 fatty acidsLDL -6-+25, non HDL -5-14, HDL -5 to +7, TG -19-44
EzetimibieLDL -13 -20, non hdl -14-19, TG -5-11, HDL +3-5
memorize

Section 2

Question Answer
statinsmuscle pain or atrophy, short term memory loss
niacinfacial flushing, hepatotoxicity, hyperglycemia, hyperuricemia
fibric acid derivativesdyspepsea, gallstones
bile acid sequestrantsbloating, can increase triglycerides
omega 3 fatty acidsfish burps, potentially increases bleeding
ezetimibepotentially increases risk of cancer
memorize

Section 3

Question Answer
statinscirrhosis
niacinactive liver disease, active ulcers
fibric acid derivativesnot to be used with statins, caution on renally impaired
bile acid sequestrantsshould not use in px with biliary obstruction, DC if TG exceds 400
omega 3- fatty acidsknown allergy to fish
ezetimibedont use with statins, px with hepatic disease
memorize

Section 4

Question Answer
statinstalk to doc if feel muscle pain
niacinmay increase BG
fibric acidsincreased bleeding
bile acidsdrink plenty of fluids
omega 3smay cause fish burps
ezetimibemay experience rhinitiis, arthralgia, diarrhea
memorize

Section 5

Question Answer
statinscontinue trying new statins if patient doesn't tolerate one, different intensities
niaciner is better because of balance of AEs
Fibric acidsfenofibrate and finofibric acid are okay with statins
bile acids sequestrantscholestyramine has unique DIs
omega 3'svacepa mayraise LDL less than others
ezetimibeN/A
memorize