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HIV Drugs

rename
uvamed's version from 2016-12-07 15:13

Section

Question Answer
AbacavirNRTI; life-threatening hypersensitivity (HLAB57)
DidanosineNRTI; pancreatitis, peripheral neuropathy, hepatic steatosis
EmtricitabineNRTI (remember lactic acidosis with all nucleosides in this class)
LamivudineNRTI
StavudineNRTI; pancreatitis, peripheral neuropathy, hepatic steatosis
TenofovirNtRTI; only nucleotide in this class
Zidovudine NRTI; BM suppression; formerly AZT; used around pregnancies
DelavirdineNNRTI; teratogen
EfavirenzNNRTI; teratogen, CNS issues (vivid dreams), pos. marijuana test
NevirapineNNRTI (recall rash/hepatotoxicity common to all members of this class)
EtravirineNNRTI
RilpivirineNNRTI
AtazanavirPI; nephrolithiasis, jaundice
DarunavirPI (recall GI intolerance, hyperlipidemia, lipodystrophy (buffalo hump) and P450 repression common to whole class)
FosamprenavirPI
IndinavirPI; nephrolithiasis
LopinavirPI
RitonavirPI; strongest cyt P450 repressor (don't use whoel class w/ rifampin), pancreatitis
SaquinavirPI
RaltegravirII (nausa, rash, myopathy present for entire class; increased creatine kinase for whole class!!)
ElvitegravirII (remember TEGravir for whole class)
DolutegravirII
EnfuvirtideFI; binds gp41; skin reaction at inj. site + bacterial pneumonia
MaravirocFI; binds CCR5; do tropism test before prescribing
memorize

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