Histology ES 3

malakissa's version from 2016-01-21 16:20


Question Answer
Adrenal Gland Composed ofouter cortex (forms 90% of it) and an inner medulla (10%)
GD TF LTR :3glomerulosa is darker than Fasciculata & lighter than Reticularis
Adrenl G capsule consist ofdense CT
zona Glomerulosaspherical cells below the capsule, 15% of cortex
zona Fasciculatalongitudinal arrangement and light in color , lipid droplets
largest part of Adrenal cortexzona Fasciculata
zona Reticularis networks, heavey stain (darkest)
Medullapale, made of chromaffin cells that are arranged as clusters
Zona Glomerulosa produces aldosterone
Zona Fasciculata produces glucocorticoids (cortisol)
Zona Fasciculata contain 1- abundant mitochondria and 2-smooth endoplasmic reticulum with numerous lipid droplets
most active cells (with numerous lipid droplets ) found inZona Fasciculata
The production of steroids needsmitochondria and SER, it doesn’t granules, so these cells contain lipid droplets instead of these granules
Adrenal cortex cellscells appear foamy-contain lipid droplets instead of granules- (can be called spongiocytes).
spongiocyte is a cell in the zona fasciculata of the adrenal cortex
Zona Reticularis produces androgens
the least active cells ( they stain more heavily) -less lipid droblets found inZona Reticularis
dark cells - stain heavily - low lipid dropletsless activity
foamy cells - stain lightly - high lipid dropletsmore active
Medulla secretes catecholamines (80% epinephrine and 20% norepinephrine)
Medullary adrenocyte “cell of the medulla”chrommafine cell
Medullary adrenocyte two types of granules epinephrine & norepinephrine
The granules of norepiniphrine is more/less electron dense than those of epinephrinemore (nor as more :) )
The main secretion of the adrenal medulla isepinephrine
norepinephrine is converted to epinephrine in themedullary adrenocytes
Cells of the zona glomerulosa are organised intosmall rounded groups or curved columns.
Cells in ZG are smaller/larger than in the two other zonessmaller
zona glomerulosa shapetheir nuclei are dark and round, and the cytoplasm is light basophilic.
zona glomerulosa is influenced by ACTH. T/FF (zona glomerulosa is not influenced by ACTH)
zona fasciculata are organised intocell cords separated by fenestrated sinusoid capillaries.
zona fasciculata cell shapeThe nucleus is light and typically located centrally. The cytoplasm is also light and often has a characteristic foamy or spongy appearance (lipid droplets in the cytoplasm extracted during tissue processing) - they are for this reason also called spongiocytes.
zona Reticularis are organised intoAnastomosing cell chords separated by sinusoid spaces
zona Reticularis Cells are typically smaller/larger than in the zona fasciculata.smaller
zona Reticularis Cells shapeTheir cytoplasm is eosinophilic and less spongy than that of other cells in the cortex & The nucleus is rather light and large
The medulla is not sharply delimited from the cortex. (T/F)T
medullary Cells are arranged in strands or small clusters.
intervening spaces in the medulla cotainsCapillaries and venules
The cytoplasm of the medullary cells is weakly/strongly basophilic/acidophilicweakly basophilic
chromaffin cells named that bcz because the granules of these cells can be stained with potassium bichromate
medullary Cells calledchromaffin cells
Chromaffin cells correspond to secretion ofthe adrenaline(80%) and noradrenalineproducing cells of the medulla.