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Hemoglobin Types

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yizucuru's version from 2015-10-19 07:58

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Question Answer
Hemoglobin Aalpha2/beta2, adult normal hemoglobin
Hemoglobin Falpha2/gamma2, fetal, higher O2 affinity
Hemoglobin Salpha2/beta2, with val substitution at Glu 6 on beta, leads to Sickle cell
Hemoglobin Calpha2/beta2, with lysine for Glu 6 on beta, mild hemolytic anemia, crystal cells
Hemoglobin SChetero for S and C, less severe than sickle
Hemoglobin Ealpha2/beta2, with lysine for Glu on 26 beta, microcytic hypochromic anemia
Hemoglobin bartsgamma tetramer, seen in alpha thalassemia
Hemoglobin Hbeta tetramer, seen in alpha thalassemia
Hgb A2alpha2/delta2, seen in beta thalassemia major
Methemoglobulinreversible oxidation to Fe3+
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