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Hematologic Malignancies

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jennifer12345's version from 2018-12-08 16:44

Section 1

Question Answer
acute leukemiarapidly growing cells, lifespan only a few months if no treatment, highly curable
chronic leukemiamature cells but not normal, slowly progressive, harder to cure
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Section 2

Question Answer
risk factors for ALL (acute lymphocytic leukemia)radiation exposure, benzene/chemo agents, viral infections EBV/HTLV, down sydnrome
risk factors for AML (acute myelocytic leukemia)smoking, benzene exposure, previous chemo, poycythemia vera, NOT familial
risk factors for CML (chronic mylogenous leukemia)radiation exposure, aging, not associated with smoking/diet/chemicals/infections
risk factors for CLL (chronic lymphocytic leukemia)exposure agent orange, farming/long term exposure pesticides, familial.
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Section 3

Question Answer
chronic leukemia presentationasymptomatic, cardinal finding: splenomegaly, fullness abd/LUQ
lymphoma presentationpainless lymphadenopathy, fever, night sweats, wt loss
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Section 4

Question Answer
diagnosis of CMLbone marrow bx with philadelphia chromosome
diagnosis of acute leukemias (ALL/AML)anemia, thrombocytopenia, wide variance in WBCs
diagnosis of hodgkins lymphomalarge, abnormal reed-sternberg cells in nodes
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Section 5

Question Answer
hodgkins lymphomaB lymphocyte cells
non hodgkins lymphomaB and T lymphocyte cells
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