Gyn Cancer Staging

bonecixa's version from 2016-09-04 07:21

Section 1

Question Answer
Stage 0Carcinoma in situ; intraepithelial carcinoma
Stage 1Cancer strictly confined to the cervix
1aMicroscopic invasive cancer-->all gross lesions are stage IB!!!!!
1a1Measured stromal invasion no greater than 3.0 mm in depth and no wider than 7.0 mm
1a2Measured stromal invasion greater than 3.0 mm and no greater than 5.0 mm in depth and no wider than 7.0 mm
1bClinically evident lesion confined to the cervix or preclinical lesion greater than IA
1b1Clinically evident lesions no greater than 4.0 cm in size
1b2Clinically evident lesions greater than 4.0 cm in size
Stage 2Cancer extends beyond the cervix but not to the pelvic sidewall, or cancer involves vagina but not as far as the lower third
2aInvolvement of vagina, but not lower third; No obvious parametrial involvement
2bInvolvement of vagina, but not lower third; not out to sidewall; Obvious parametrial involvement
Stage 3Cancer has extended to pelvic sidewall and/or tumor involves lower third of the vagina and/or hydronephrosis and/or nonfunctioning kidney
3aTumor involves lower third of vagina; no extension to pelvic sidewall
3bExtension to pelvic sidewall and/or hydronephrosis or nonfunctioning kidney
Stage 4Extension beyond the true pelvis or clinically involving mucosa of bladder or rectum
4aSpread to mucosa of (bladder or rectum)
4bDistant metastasis outside the true pelvis

Section 2

Question Answer
How is cervical cancer staged?Clinically (and once assigned a stage, it can not/will not be changed based on additional findings)
How is endometrial cancer staged?Surgically
How is breast cancer staged?TNM
How is vulvar cancer staged?Surgically
How is vaginal cancer staged?Clinically

Section 3

Question Answer
Stage 1limited to one or both ovaries
1ainvolves one ovary; capsule intact; no tumor on ovarian surface; no malignant cells in ascites or peritoneal washings
1binvolves both ovaries; capsule intact; no tumor on ovarian surface; negative washings
1ctumor limited to ovaries with any of the following: capsule ruptured, tumor on ovarian surface, positive washings/cells in ascites
Stage 2pelvic extension or implants
2aextension or implants onto uterus or fallopian tube; negative washings
2bextension or implants onto other pelvic structures; negative washings
2cpelvic extension or implants with positive peritoneal washings
Stage 3peritoneal implants outside of the pelvis; or limited to the pelvis with extension to the small bowel or omentum
3amicroscopic peritoneal metastases beyond pelvis. negative nodes
3bmacroscopic peritoneal metastases beyond pelvis less than 2 cm in size
3cperitoneal metastases beyond pelvis > 2 cm or positive retroperitoneal or inguinal lymph nodes
Stage 4distant metastases to the liver or outside the peritoneal cavity,pleural effusion contains evidence of metastases , parenchymal liver involvment

Section 4

Question Answer
1aTumor is confined to the uterus with less than half myometrial invasion
1bTumor is confined to the uterus with more than half myometrial invasion
Stage 2Tumor involves the uterus and the cervical stroma
3aTumor invades serosa or adnexa
3bVaginal and/or parametrial involvement
3c1Pelvic lymph node involvement
3c2Para-aortic lymph node involvement, with or without pelvic node involvement
4aTumor invades bladder mucosa and/or bowel mucosa
4bDistant metastases including abdominal metastases and/or inguinal lymph nodes

Section 5

Question Answer
Name the main histologic subtypes of Ovarian epithelial tumors? (6)serous, endometrioid, mucinous, clear cell, Brenner, and undifferentiated
What percent of Ovarian cancers are serous?35-40%
What percent of Ovarian cancers are endometriod?15-25%
What percent of Ovarian cancers are mucinous?6-10%
What percent of Ovarian cancers are clear cell?5%
What percent of Ovarian cancers are Brenner?<1%
What percent of Ovarian cancers are Undifferentiated?15-30%
Most serous, mutinous, and Brenner tumors are benign...true or false?True
Almost all endometrioid and clear cell tumors are malignant...true or false?True
What is the most common malignant epithelial ovarian tumor?Serous 80-90% (followed by mutinous & endometriod at 10% each)
Serous tumors look like what, histologically?fallopian tubes