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GOUT

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munsele's version from 2016-06-30 00:43

Section

Question Answer
Short-term steroid SEfeeling spacey, insomnia, hyperglycemia
Colchicine dosing1.2mg followed by 0.6mg in 1h NTE 1.8mg in 1h or 2.4mg/day
Gout risk factorsMale, obese, hypertensive, alcohol consumption, CKD, lead intoxication, advanced age
How to reduce risk of recurrent attacksavoid organ meats, high fructose corn syrup, and alcohol
Normal uric acid level 2-7.2mg/dL
Goal uric acid<6
Tx for acute attackColchicine, NSAID, or steroid
How soon until you can repeat colchine dosing3 days
Pegloticase Pearls and brandKrystexxa for refractory cases only, monitor for anaphylaxis
Probenecid blocks renal clearance ofASA, MTX, PCNs, cephs, and carbapenems
Allopurinol SEwatch for rash! SJS or TEN
Meds that elevate uric acidNiacin, Diuretics, cyclosporine, tacrolimus, ASA, ribavirin, pyrazinamide
Agents for gout prophylaxisAllopurinol, febuxostat, probenacid
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