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GIT- liver pathology

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drnieves's version from 2017-06-20 00:28

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Question Answer
Dubin johnson syndromeDefective hepatic excretion of bilirubin glucoronides across the canalicular membrane= direct hyperbilirubinemia and jaundice.
Liver appears blackDue to impaired excretion of epinephrine metabolites, dense pigments within lysosomes. Dubin johnson.
Hep AFever, malaise, GOT, RUQ pain and signs of cholestasis (jaundice, pruritus, dark coloured urine, clay stools).
CholecystitisFrom cholelithiasis (gallstones) blocking cystic duct. Normally, is a 2nd infection.
Cholecystitis sxMurphy +, RUQ pain, Increased in ALP if bile duct involved.
Ultrasound, cholescintigraphy, hepatibiliary iminodiacetic acid scanCholecystitis dx
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