G protein linked 2nd messengers

jholbert's version from 2016-02-29 20:58


Question Answer
Alpha-1 (q):INCREASES vascular smooth muscle contraction, pupillary dilator muscle contraction (mydriasis), intestinal and bladder sphincter muscle contraction
Alpha-2 (i):DECREASES sympathetic outflow, insulin release, lipolysis, aqueous humor production, INCREASES platelet aggregation
Beta-1 (s): INCREASES heart rate, contractility, renin release, lipolysis
Beta-2 (s): Vasodilation + bronchodilation; INCREASES HR, contractility, lipolysis, insulin release, aqueous humor production, and DECREASES uterine tone (tocolysis)
M1 (q): CNS, enteric nervous system
M2 (i): DECREASES heart rate and atrial contractility
M3 (q): INCREASES exocrine gland secretion (sweat/gastric acid), gut peristalsis, bladder contraction, bronchoconstriction, pupillary sphincter muscle contraction (miosis), ciliary muscle contraction (accommodation)
D1 (s):Relaxes renal vascular smooth muscle
D2 (i): Modulates transmitter release (brain)
H1 (q): INCREASES nasal and bronchial mucus production, contraction of bronchioles, pruritus, and pain
H2 (s): INCREASES gastric acid secretion
V1 (q): INCREASES vascular smooth muscle contraction
V2 (s): INCREASES H2O permeability and reabsorption in the collecting tubules of the kidney (V2 in the TWO kidneys)