sapete21's version from 2015-10-05 14:46

Section 1

Question Answer
Megaloblastic AnemiaFolic Acid, tetrahdrofolic acid, syn. methionine, purines, dTMP, neural tube defects
VValine (val) Branched Chain Nonpolar
PProline (Pro) ring, bulky, nonpolar, sterically hinders structures
Vitamin Ealphatocopherol, Antioxidant, Rare disorder
Vitamin KMenadione, Menaquinone, Phylloquinone, Gama-carboxylation of glutamate resides in clotting, common in newborns
RicketsVitamin D (cholecalciferol); 1,25Dihydroxy-cholecalciferol; Calcium uptake, gene expression; rickets (kids), osteomalacia (adults)
XerophthalmiaVitamin A (beta-carotene, retinol, retinoic acid); reproduction, vision, growth; infertility, night blindness, retardation of growth
Pantothenic AcidCoenzyme A, Acyl Carrier, Rare
biotin enzyme biotin, cofactor for carboxylation reactions (pyruvate carboxylase, acetyl coA carboxylase) - rare
RiboflavinVitamin B2; FMN/FAD; electron transfer, rare deficiency

Section 2

Question Answer
DAspartate (asp), Acidic, Negative
CCysteine (cys); Sulfur containing
EGlutamate (glu); Negative, Acidic
PellagraNiacin (nicotinic acid, nicotinamine); NAD, NADP; Electron Transfer
Wernicke-KorsakoffVitamin B1 (Thiamine); Thaimine pyrophosphate; Coenzyme in PDC, AKGDH, Transketolase, BCAA DH; BeriBeri + Alcoholics
Vitamin B6Pyridoxine; PLP(Byridoxal phosphate); coenzyme for AA metabolism, aminotransferases; very rare
ScurvyVitamin C; Ascorbic Acid; Antioxidant, coenzyme for prolyl hydroxylase, required for collagen synthesis
SSerine (ser) Polar, Uncharged
QGlutamine (Gln) Polar, Uncharged
Pernicious AnemiaVitamin B12 (Cobalamin); methylcobalamin; Coenzyme for conversion of homocysteine to methionine, methylmalonyl CoA to succinyl coA; dementia and spinal degredation
Lineweaver-Burk1/Vo=km/vmax(s) + 1/Vmax; Slope = km/vmax; Y intercept: 1/Vmax; X intercept: 1/km
1st order enzyme[S]<<<
[S[>>>Km : V=Vmax; Zero Order doesn't depend on s

Section 3

Question Answer
NAsparagine (Asn); Polar Uncharged
WTryptophan (Trp); 2 rings, polar, aromatic
Ytyrosine (tyr); polar, aromatic
Homotropic Effectorssubstrate itself serves as an effector "cooperative binding"
km[substrate] at which 1/2Vmax is reached; affinity (low Km=high affinity...)
MMethionine (Met); sulfur
TThreonine (thr; polar uncharged
Michaeless Menton EquationVo= (vmax(s)/(km+s))
Aalanine (ala)- nonpolar alipathic (methyl group)
FPhenylalanine (phe) - nonpolar aromatic
Hhistidine (his), positive basic
IIsoleucine (ile); branched chain, nonpolar, alipathic
Klysine (lys); positive, basic
L leucine (leu); branched chain, nonpolar, alipathic
RArginine (arg); positive basic
GGlycine (gly); non polar; hydrogen