Create
Learn
Share

Fluid Lecture Treatment of SIAD

rename
alchemist04's version from 2016-08-09 02:33

Section

Question Answer
ConivaptanVaprisol
TolvaptanSamsca
DemeclocyclineTetracyclin Antibiotic
memorize

 

Question Answer
What is the direction for Conivaptan?(1) Give 20 mg IV load dose (over 30 mins) (2) Followed by continuous infusion of 20 mg for 24 hrs (3) may titrate up to 40 mg/ day if result is unsatisfactory
The duration of Conivaptan must not exceed ----- days4 days
What are the side effects of Vaprisol?Phebitis, thirst and hypotension (PTH)
What is the MOA of Vaprisol?Mixed V1a + V2 receptor antagonist
memorize

 

Question Answer
What is the direction for Tolvaptan?(1) Initial dose 15 mg PO QD (2) Double dose every 24 hrs if no response/unsatisfactory (3) Max at 60 mg PO QD
The max for Samsac is -----60 mg PO QD
What is the Black Box warning for Tolvaptan?Must be administered in the hospital for Sodium monitoring.
Duration of therapy for Tolvaptan must not exceed?30 days
What is the MOA of Tolvaptan?Selective Oral V2 receptor antagonist
memorize

 

Question Answer
Which of these warning is applicable to Samsac? (a) avoid in pt that are unable to sense or respond appropriately to thirst (b) avoid in pt taking strong CYP 3A4 inhibitors (c) Avoid in patient with hypovolumeric hyponatremia (d) avoid in pt needing rapid correction of serum sodium (e) Avoid in pt with hyperglycemia (f) Avoid in pt with polyuriaAns are a-d
Which of these medications could cause hepatotoxicity? (a) Tolvaptan (b) Conivaptan (c) Samsac (d) VaprisolTolvaptan and Samsac (both are the same)
Which of the ff meds carry a Black Box Warning (BBW) of "must be administered in the hospital to monitor sodium level" (a) TolVaptan (b) Samsac (c) Demeclocycline (d) Conivaptan (e) VaprisolAns is Tolvaptan and Samsac (both are the same)
What are the side effects of Conivaptan?Phenibitis, thirst and hypotension (PTH)
What are the side effects of Tolvaptan?Polyuria, Thirst, Dry mouth, Constipation and hyperglycemia (PTD CH)
memorize

 

Question Answer
What is the MOA of Demeclocyclin?Diminish tubular responsiveness of ADH
What is the usual dose of Demeclocyclin?300 mg PO 2-4x QD
T or F? Demclocycline interfers with bone development?True
T or F? Demeclocycline must be avoided in childrenTrue
Demeclocycline could cause risk of hepatotoxicity or renal toxicity?Hepatotoxicity
memorize