Fluid Disorder Lecture 1 Part 1 TBW

alchemist04's version from 2016-06-21 05:44


Question Answer
TBWTotal body water
TBW (f)0.5 * Weight of Female (Kg)
TBW (m)0.6 * Weight of Male (Kg)


Question Answer
T or F? % TBW decreases as with age and increase in body fatTrue
If a pt is Obese (>30% over IBW), use ----------Use Ideal Body Weight (IBW)
IBW (f) in Kg45.5 + 2.3 (height in inches - 60)
IBW (m) in Kg50 + 2.3 (height in inches - 60)


Question Answer
ICF isWater inside the cell and rich in (1) Protein (2) Potassium (3) Phosphate (4) Magnesium. It is the 2/3 of TBW
ECF isFluid outside the cell it contains (1) Interstitial Fluid (2) Intravascular Fluid. It is 1/3 of TBW
Interstitial FluidFluid occupying the spaces btw the cells. It is 3/4 of ECF.
Intravascular FluidFluid w/n the blood vessels, also known as plasma. It is 1/4 of ECF


Question Answer
ICF is ----- of IBW2/3
ECF is ------ of IBW1/3
Interstitial Fluid is ------ of ECF3/4
Intravascular is ------- of ECF1/4


Question Answer
What is Normal Serum Osmolality?~ 285 - 293 mOm/kg
What are the main solutes of Plasma/serum?(1) Sodium (2) Glucose (3) Urea
Serum Osmolality (mOsm/kg)= 2 [Na+ (mEq/L)] + [Glucose (mg/dL)] / 18 + [BUN (mg/dL)] / 2.8


Question Answer
T or F? Sodium is the main determinant of plasma tonicityTrue, it is confined to ECF
T or F? Glucose do not make large contribution to plasma tonicityTrue, however, if uncontrolled could lead to diabetics which could cause significant change in tonicity
T or F? Urea is isotonic and does not contribute to plasma tonicityTrue, Urea also moves freely across compartments


Question Answer
Transcellular fluid comprises of ......... ?Viscous components of the (1) Peritoneum (2) Pleural space (3) Pericardium (4) joint space fluid (5) digestive juice
Tranxcellular fluid is normally ------- % of TBW1% and can go up in case of sickness
Third Spacing isaccumulation of fluid in the transcellular space.


Question Answer
What are ways in which water balance are maintained (Homeostasis) (1)(1) Thirst mechanism
What are ways in which water balance are maintained (Homeostasis) (2)(2) RAAS ( Renin-Angiotensin-aldosterone system)
What are ways in which water balance are maintained (Homeostasis) (3)(3) ADH (Anti Diuretic Hormone), aka Vasopressin or Arginine Vasopressin (AVP
What are ways in which water balance are maintained (Homeostasis) (4)(4) ANP (Atrial Natriuretic peptide)


Question Answer
Thirst mechanism stimulates --------desire to drink fluid
RAAS, In volume depleted state, (1) --------- and (2) ---------- delivery to the kidney (3) ---------------- ---> release of (4) -------------- ----> activation of (5) --------------- ---> release of Aldosterone (urinary sodium and water reabsorption) and (6) --------- (water reabsorption)(1) GFR (2) Sodium (3) decreases (4) renin (5) RAAS (6) ADH
ADH also known asVasopressin or Arginine vasopressin
ADH can be stimulated independent of --------RAAS
ADH promotes insertion of (1) --------- into the (2) -------- membrane of (3) -------------- cells in the (4) ---------------- ducts of nephron of kidney(1) aquaporous (water channel protein) (2) Apical membrane (3) Principal cells (4) Collecting ducts
ADH increase -----------Urinary water reabsorption
ANP increasesurinary sodium and water excretion