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First Aid - Cell Surface Proteins

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zubegedo's version from 2017-03-16 01:34

Cell Surface Proteins

Cell Surface ProteinExpressed onNotes
MHC IAll cellsAll cells, except mature RBCs have MHC I
TCR T-cellsBinds antigen-MHC complex
CD3T-cellsAssociated with TCR for signal transduction
CD28T-cellsBinds B7 on APC
CD4TH cellsBinds MHC II
CD40 ligandTH cellsbinds to CD40 on B cells to activate them
CD8Cytotoxic T-cellsBinds MHC I
IgsB-cellsBind antigens
CD19B-cells
CD20B-cells
CD21B-cellsReceptor for EBV (You can drink Beer at Epstein's Bar when you're 21: B cells, Epstein-Barr virus; CD-21)
CD40B-cells, Macrophages
MHC IIB-cellsBinds CD4 on TH-cells
B7B-cells, MacrophagesCD28 binds B7 on APC
CD14MacrophagesCo-receptor to detect LPS- innate immune system
Fc ReceptorsMacrophagesEnhance phagocytosis
C3b ReceptorsMacrophagesEnhance phagocytosis
CD16NK cellsBinds Fc of IgG
CD56NK cellsUnique marker for NK cells
memorize

CDs

CDs (ligands)Expressed onNotes
CD3T-cellsAssociated with TCR for signal transduction
CD4TH cellsBinds MHC II
CD8Cytotoxic T-cellsBinds MHC I
CD14Macrophages
CD16NK cellsBinds Fc of IgG
CD19B-cells
CD20B-cells
CD21B-cellsReceptor for EBV (You can drink Beer at Epstein's Bar when you're 21: B cells, Epstein-Barr virus; CD-21)
CD28T-cellsBinds B7 on APC
CD40B-cells, Macrophages
CD40 ligandTH cells
CD56NK cellsUnique marker for NK cells
memorize

 

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