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FA CK Rapid Review Drug SE's

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nolucknav's version from 2017-06-06 19:07

Section

Question Answer
ACE InhibitorsCough, rash, proteinuria, angioedema, taste changes, teratogenic effects
AmantadineAtaxia, Livedo Reticularis
AminoglycosidesOtotoxicity, nehprotoxicity (ATN)
AmiodaroneActe: AV block, hypotension, bradycardia Chronic: pulmonary fibrosis, peripheral deposition leading to bluish discoloration, arrhythmias, thyroid probs, corneal deposition
AmphotericinFever/Rigors, nephrotoxicity, bone marrow suppression, anemia
AntipsychoticsSedation, acute dystonic reaction, akathisia, parkinsonism, tradive dyskinesia, NMS
AzolesP450 inhibitors
AZTThrombocytopenia, megaloblastic anemia
Beta blockersAsthma exacerbation, masking hypoglycemia, impotence, bradycardia, AV block, CHF
BenzodiazepinesSedation, dependance, respiratory depression
Bile Acid ResinsGI Upset, malabsorption of vitamins/meds
CarbamazepineP450 inducer, agranulocytosis, aplastic anemia, AV block, CHF
CCB'sPeripheral edema, constipation, cardiac depression
ChloramphenicolGrey baby syndrome, aplastic anemia
CisplatinNephrotoxicity, acoustic nerve damage
ClonidineDry mouth, severe rebound headache and hypertension
ClozapineAgranulocytosis
CorticosteroidsMania, hyperglycemia, immunosuppression, bone mineral loss, thinning of skin, easy bruising, myopathy, catarcts
CyclophosphamideMyelosupression, hemorrhagic cystitis
DigoxinGi disturbances, yellow visual changes, arrhythmias
DoxorubicinCardiotoxicity
Ethyl AlcoholAcidosis, renal dysfunction, CNS depression
FluoroquinolonesCartilage damage in children, achilles tendon rupture in adults
FurosemideOtotoxic, Hypokalemia, Nephritis, Gout
Isopropyl alcoholCNS depression, disconjugate gaze, absent ciliary reflex
Ethylene glycolFlank pain, hematuria, oliguria, CN palsies, tetany, anion gap MA
MethanolVisual blurring/Blindness, central scotoma, afferent pupil defects, AMS
GemfiborzilMyosistis, reversible increase in LFT's
HalothaneHepatotoxicity, malignant hyperthermia
HCTZhypokalemia, hyponatremia, hyperuricemia, hyperglycemia, hypercalcemia
StatinsMyosistis, reversible increase in LFT's
HydralazineDrug induced lupus
hydroxycholorquineretinopathy
INHperipheral neuropathy secondary to B6 deficiency, hepatotoxicity, inihibits p450,seizures with OD, hemolysis G6PD deficiency
MAO inihibitorsHypertensive tyramine reaction
methotrexatehepatic fibrosis, pneumonitis, anemia
methyldopa+coombs test, drug induced lupus
metronidazoleDisulfiram like rxn, vestibular dysfunction, metallic taste
Niacincutaneous flushing
nitroglycerinhypotension, tachycardia, headache, tolerance
penicillaminedrug induced lupus
penicillin/Beta-LactamsHypersensitivity rxn's
phenytoinnystagmus, diplopia, ataxia, arrhythmia, gingival hyperplasia, hirsuitism, teratogenic effects
PrazosinFirst dosse hypotension
PTUagranulocytosis, aplastic anemia
QuinidineCinchonism (Headache/Tinnitus), thrombocytopenia, arrhythmias
ReserpineDepression
RifampinP450 inducer, orange/red secretions
Salicylates Fever, hyperventilation (Resp alk and met. acid) dehydration, diaphoresis, hemorrhagic gastritis
SSRI'sanxiety, sexual dysfunction, serotonin syndrome if taken with MAOI's
SuccinylcholineMalignant hyperthermia, hyperkalemia
TCA'sSedation, coma, anticholinergic SE's, seizure, prolonged QRS, arrhythmias
Tetracyclinestooth discoloration, photosensitivity, fanconi syndrome, gi distress
TMPMegaloblastic anemia, leukopenia, granulocytopenia
valproic acidteratogenicity leading to NTD's, rare fatal hepatotoxicity
Vancomycinnephrotoxic, ototoxic, red man syndrome
vinblastinesevere myelosuppresion
vincristimeperipheral neuropathy, paralytic ileus
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