Exam Review - Chapter 33

lebohese's version from 2018-04-25 01:54

Section 1

Question Answer
Diabetes Mellitus is a disorder of ___ that involves glucose utilizationmetabolism
Blood glucose levels are regulated by hormone secretion by α-cells and β-cells in the islets of Langerhans located in the ___pancreas
When blood glucose levels rise, β-cells secrete ___insulin
When blood glucose levels fall, α-cells secrete ___glucagon
This type of diabetes has impaired fasting glucose, impaired glucose tolerance and increased risk factor for CDPrediabetes
This type of Diabetes is an autoimmune Disease; immune system attacks and destroys B-CellType 1 Diabetes
IDDM stands for?Insulin Dependent Diabetes Mellitus
Most common type of Diabetes;Type 2 Diabetes
NIDDM stands for?Non-Insulin-Dependent Diabetes Mellitus
This type of Diabetes occurs in about 3% to 8% of all pregnant womenGestational Diabetes
Fasting blood glucose test: test after?8-hr fast
Oral Glucose Tolerance Test is taken after ___ containing 75g of glucose dissolved in water2 hrs
Ketoacidosis is a complication for which type of diabetes?Type 1 Diabetes
Insulin is used to treat ___ of diabetesall types
Insulin is manufactured from which animals?Pig and Cow
Sulfonylureas are also called ___ (OHA's)Oral Hypoglycemic Agents
Which class does Biguanides fall into?Antidiabetic agents
The MOA for this drug includes increasing peripheral glucose uptake ad utilization in skeletal muscles and adipose tissuebiguanides
Alpha-glucosidase inhitors prolong the digestion of ___ and delay their absorption in the small intestineCarbohydrates
Alpha-glucosidase inhibitors ___ peak plasma glucose levelsreduce
Alpha-glucosidase inhibitors ___ promote insulin secretiondo not
Meglitinides ___ promote insulin secretiondo
Common ending for Meglitinides is ___"Glinide"
Common ending for Thiazolidinediones is ___"Glitazone"
Thiazolidinediones are also called ___insulin sensitizers
Thiazolidinediones are used in which type of diabetes?Type 2 Diabetes
Thiazolidinediones MOA include ___ uptake of glucose in the liver and muscles and ___ plasma glucose concentrationIncrease, Reduce
Dipeptidyl Peptidase-4 Inhibitor (DPP-4) ___ insulin release and ___ glucagon levelsIncrease, Reduce
Incretin Mimetic MOA include stimuation of glucagon-like peptide recepors in the ___ and ___ cells in the pancreasalpha and beta
Beta-cell stimulation for incretin mimetic ____ insulin secretion when glucose levels are elevatedstimulate
Alpha-cell stimulation ____ glucagon releasesuppress
The condition of elevated blood glucose levels is termed ___hyperglycemia

Section 2