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Exam 3 Glycogen

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rwhittaker1's version from 2017-11-12 05:45

Section 1

Question Answer
What are the 2 linkages composing glycogen molecules?alpha-1,4 and alpha-1,6 glycosidic linkages
Where is a alpha-1,4 glycosidic linkage? alpha-1,6?alpha-1,4 linkages are between glucosyl residues on the same chain, alpha-1,6 linkages are between glycosyl residues of branching chains
Function of Glycogen Phosphatase degrades alpha-1,4 bonds via phosphorolysis, produces glucose-1 phosphate
Function of Transferaseshifts a block of glucosyl residues, exposing a glucose with an alpha-1,6 linkage
Function of alpha-1,6 glucosidasehydrolyzes alpha-1,6 branch, releases a free glucose
Function of phosphoglucomutaseconverts glucose-1 phosphate to glucose-6 phosphate, utilizes glucose-1,6-bisphosphate as an intermediate
Function of Glycogen synthaseadds glucose to a UDP primer, synthesizes alpha-1,4 bonds
Function of Branching enzymegenerates branches by cleaving an alpha-1,4, transferring a block of 7 glucoses, and anchoring them to another glucose chain by synthesis of an alpha-1,6 bond
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Section 2

Question Answer
Key regulatory enzyme between glycolysis and gluconeogenesis?Protein Phosphatase 1
Function of Protein Phosphatase 1shifts glycogen metabolism from lysis to synthesis
Function of glucagon and epinephrineEpinephrine/glucagon causes the activation of protein kinase A, which inactivates PP1 ceasing glycogen synthesis
Function of InsulinStimulation of glycogen synthesis by inactivation of glycogen synthase kinase
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