include helix-turn-helix (HTH, green in top image below), zinc finger (blue in middle image) and basic-region leucine zipper (bZIP, blue in bottom image).
don't age because they protect their genetic information by preventing telomeres from degrading, they grow uncontrolled, dividing due to failure to respond to cellular controls.
avoid apoptosis that normally occurs during extensive DNA damage. stimulate angiogenesis causing new blood vessels to grow nourishing the cancer cell. metastasize (begin growing in new locations) like Starbucks.
cause cancer when activated, mostly by speeding up cell division.start as proto-oncognes and are harmless until triggered
can cause cancer
genes slow down or control cell division. If the suppressor fails to function, cancer occurs.
are the important information in RNA
are not needed (so they are removed by a spliceosome in RNA splicing)
5' caps and 3' poly-A tails
are added after transcription to protect the RNA from breaking down.
near the GU sequence, causes a loop, a spliceosome cleaves the intron at the 5' GU sequence (forming a lariat at the AG branch site), the 3' end of the intron is cleaved at the AG sequence and the two exons are ligated together.