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Endocrine- pharm

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drnieves's version from 2017-06-20 12:59

Section

Question Answer
Rapid acting insulinAspart, glulisine, Lispro
Injected insulin MOAbrinds R= tyrosine kinase. Increase glycogen in liver. Increase glycogen, protein synthesis and K uptake in muscle. Increase TG storage in fat.
Rapid acting insulin ADRHypoglycemia, hypersensitivity
Rapid acting insulin use1, 2 and postprandial.
Short acting insulinRegular
Short acting insulin use1, 2, postprandial, DKA, hyperkalemia, stress hyperglycemia.
Insulin intermediate acting NPH
Insulin intermediate acting use1,2, postprandial.
Long acting insulinDetemir, Glargine
Long acting insulin use1,2, postprandial
ThionamidesMethimazole, propylthiouracil
Inhibit thyroid peroxidase (iodine organification and coupling of iodotyrosines)Thionamides
PropylthiouracilDecreases T4 to T3
HHARTAss with body fat redistribution.
Subcutaneous lipoatrophy assnucleoside reverse transcriptase inhibitors (stavudine/ zidovudine) and protease inhibitors.
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