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Emory SOM Pharmacology Review

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Updated 2008-08-17 23:37

Drugs!

DrugDescription
LevothyroxineTH replacement
LiothyroxineAcute severe hypothyroid
Thioureylenesinactivates thyroid peroxidase
propylthiouracilthioureylene
methimazolethioureylene
Lugol's solutionlow dose stimulatory, high inhibitory
synthroidTH replacement, same as levothyroxine
somatotropinrecombinant GH
somatremrecombinant GH
octreotideselective somatostatin analog
bromocriptinedopamine agonist
pergolinedopamine agonist
cabergolinedopamine agonist
desmopressinVP analogue
PitressinVP analogue, stop GI bleeding
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Diabetes

Question Answer
thiazolidinedionesbroad; increase insulin sensitivity
sulfonylureaincrease insulin secretion
metformindecrease hepatic glucose production
biguanidesincludes metformin
glinidesincrease insulin secretion
alpha-glucosidaseinhbiit glucose absorption
stigaliptinDPP4 inhibitor (incretin increase)
lisprovery short insulin
aspartvery short insulin
NPHintermediate insulin
detemirlong 14 hr insulin
glarginelong 22 hr insulin
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Erectile Dysfunction

Question Answer
Viagraincrease cGMP --> NO
CialisInhibit PDE5 --> NO
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Normal Hematology Values

Question Answer
Hemoglobin (male)15.5 ± 1.5g/dL
Hemoglobin (female)13.8 ± 1.5g/dL
Hematocrit (male)47 ± 5%
Hematocrit (female)42 ±5 %
RBC Count (male)5.4 E6/microL
RBC Count (female)4.8 E6/microL
Leukocytes5000 - 11000 / microL
Neutrophils4000 - 6000 / microL
Eosinophils<450 / microL
Basophils<50 / microL
Lymphocytes2000 - 5000 / microL
MCV90 ± 9 fl
MCH32 ±2 pg/cell
MCHC33± 3 g/dL
RDW13 ±1
Reticulocytes50000 ± 25000 /microL
Platelets140000 - 450000 /microL
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