1. Protect the drug from environment, eg, air, moisture, light. 2. Mask unpleasant taste and odor. 3. Easier swallowing 4. Improve product identity. 5. Minimize cross contamination due to powder dust generated during high-speed packaging operations. 6. Improve product appearance. 7.Reduce incompatibility between drugs in the tablet. 8.Reduce abrasion and attrition. 9.Modify drug-release, as in enteric-coated products.
what is primarily used for sugar coating?
why is sucrose primarily used for sugar coating?
• Sucrose is one of the few materials that produce smooth, high-quality coating that is basically dry and tack (stickiness)-free at the completion of the coating process.
tablets, powders, granule, nonpareils, and capsules.
how is film coating applied?
continuously by spraying the coating liquid onto a moving mass of product.
why was the film coating technique introduced in the 1950's?
because ofthe shortcomings of the sugar coating process that was predominantly used.
what are the five advantages of film coating?
1.• Minimal weight increase (usually 2-3% of tablet core weight). 2.• Much shorter processing time. 3.• Increased process efficiency and output. 4. • Increased flexibility in formulations. 5. • Improved resistance to chipping of the coat.
• In the early years of film coating, ________________ solvents were used to enhance evaporation and decrease processing time.
volatile organic solvents
• Due to significant improvements in the equipment technology, _______________coating liquids are used nowadays.
What has replaced conventional pans which are faster at drying?
side-vented pans and fluid-bed equipment
what are the materials used in film coating?
• Polymer, plasticizer, colorant, and vehicle.
Each white to off-white, oval, film-coated FACTIVE tablet has breaklines and GE 320 debossed on both faces and contains?
gemifloxacin mesylate equivalent to 320 mg gemifloxacin