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Drug Classes for Pharm - Block III

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darodri6's version from 2016-05-03 22:45

Section

Drug ClassDrugs
Drugs that inhibit platelet aggregationaspirin
clopidoGREL
eptiFIBatide
Drugs impacting clotting factors (anti-coagulants)Warfarin
Dabigatran
Heparin
Eonxoaparin
Fondaparinux
Antidote for Heparin (an anti-coagulant)Protamine
Antidote for Warfarin (a drug that impacts clotting factors)Phytonadione = Vitamin K
FibrinolyticAltepase
Antidote for Altepase (a fibrinolytic)Tranexamic acid
Diureticsacetazolamide
furosemide
hydrochlorothiazide
amiloride
spironolactone
mannitol
Drugs impacting vasopressin aka ADH (agonists)vasopressin
desmopressin
Drugs impacting vasopressin aka ADH (antagonist)tolvaptan
Brain natriuretic peptide analog (diuretic)nesiritide
Neprilysin inhibitor (diuretic)secubitril
Calcium channel blockersDiltiazem
verapamil
amlodipine
Direct vasodilatorshydralazine
minoxidil
ACE inhibitorsLisinopril
Angiotensin receptor blocker (ARBs)Losartan
Nitric oxide donorsNitroglycerin
isosorbide mononitrate
nitroprusside
PDE5 inhibitorSildenafil
Class I antiarrhythmics: Na channel blockersIa: procainamide, quinidine
Ib: lidocaine
Ic: proprafenone
Class II: beta blockersEsmolol
Metoprolol
Class III: K channel blockersAmiodarone
Ibutilide
Class IV: Calcium channel blockersVerapamil, Diltiazem
Miscellaneous antiarrhythmic drugsAdenosine
Digoxin
Magnesium
Antidote for Digoxin (an antiarrhytmic drug)immune Fab
Drug for Hypokalemiapotassium chloride, and magnesium
Drugs for HyperkalemiaStabilize Na+ cells:
calcium chloride, calcium gluconate
Shift K into cells:
Albuterol, Sodium bicarbonate, insulin + glucose
Remove K from body:
furosemide, sodium polystyrene sulfonate
1st generation H1 AntihistamineDiphenhydramine,
Chlorpheniramine
2nd generation H1 AntihistamineLoratidine,
Cetirizine
3rd generation H1 AntihistamineFexofenadine
H2 AntihistaminesCimetidine,
Famotidine
EicosanoidsMifepristone,
Misoprostol,
Alprostadil,
Epoprostenol
Eicosanoid AntagonistsCorticosteroids (hydrocortisone, prednisone, etc),
Montelukast,
NSAIDS,
ASA (aspirin),
Non-Specific NSAIDS (Diclofenac, Ibuprofen, Indomethacin, Naproxen),
COX-2 Specific NSAIDS (Celecoxib = selective for COX-2; Meloxican = preference for COX-2)
TNFa Inhibitors (immunosuppressants)Etanercept,
Infliximab
Calcineurin inhibitors (immunosuppressants)cyclosporin A,
tacrolimus
mTOR inhibitors (immunosuppressants)Sirolimus
Inhibitor of lymphocyte proliferation (immunosuppressants)Azathioprine (prodrug of 6-mercaptopurine)
Inhibitor of dihydrofolate reductase aka DHFR (immunosuppressant)Methotrexate
antidote for Methotrexatefolinic acid
Inhibitor of Guanosine (immunosuppressant)Mycophenolate
Inhibitor of pyrimidine synthesis (immunosuppressant)Leflunomide
Hematopoietic Growth Factor that induces erythropoiesisEpoetin alfa
Hematopoietic Growth Factor that induces Myeloid Growth Factors (neutrophil count)Filgrastim,
Pegfilgrastim
Direct Anti-Xa InhibitorsRivaoxaban,
edoxaban,
apixaban
Cell Cycle-Specific Agents that are Anti-metabolites (S phase)Cytarabine,
5-Fluorouracil,
6-Mercaptopurine,
Methotrexate
Cell Cycle-Specific Agents that are Topoisomerase II inhibitors (G1-S Phase)Etoposide
Cell Cycle-Specific Agents that are Topoisomerase I inhibitors (S Phase)Irinotecan
Cell Cycle-Specific Agents that are Taxanes (M Phase)Paclitaxel
Cell Cycle-Specific Agents that are Vinca alkaloids (M Phase)Vincristine
Cell Cycle-Specific Agents that are Anti-tumor Antibiotics (G2-M Phase)Bleomycin
Cell Cycle-Specific Agents that is a Ribonucleoside Reductase InhibitorHydroxyurea
Cell Cycle-Nonspecific Agents that acts as an Alkylating AgentCyclophosphamide,
Ifosfamide,
Busulfran
Cell Cycle-Nonspecific Agent that act as Platinum AnalogsCarboplatin,
Cisplatin
Cell Cycle-Nonspecific Agent that act as AnthracyclinesDoxorubicin
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