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Diffuse Parenchymal Lung Disease

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hwilliam50's version from 2015-10-19 14:07

DPLD Epidemiology

Question Answer
AIPacute, 5 and 6 decade
IPFsubacute, 6 decade, former smokers, M>F
NSIPsubacute , 5 decade, some related to CVD (classic: 50yoF nonsmoker)
DIPsubacute, 4 decade, current heavy smoker
COPsubacute, 5 and 6 decade, M=F
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DPLD Radiology

Question Answer
AIPDiffuse alveolar filling pattern
IPFReticulation, honeycombing
NSIPReticulation, less honeycombing
DIPGround glass, some reticulation
COPPatchy alveolar pattern
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DPLD Pathology

Question Answer
AIPAlveolar wall thickening, type II pneumocyte hyperplasia, hyaline membranes
IPFPatchy; nonuniform, temporal heterogeneity
NSIPTemporal uniformity of lymphocytic interstitial inflammation
DIPDiffuse, uniform - dirty macrophages
COPPolypoid plugs of loose organizing connective tissue within airspaces
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