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CYP 450 (v 1.0)

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kakixaxu's version from 2017-09-07 18:32

Section

DrugCYP interaction
diltiazem3A4 substrate/BIG inhibitor
pimozide1A2 substrate
irbesartan2C8 inhibitor
fluvastatin2C9 substrate
voriconazole2C19 substrate/inhibitor, BIG 3A4/2C9 inhibitor
venlafaxine3A4/2D6 substrate
nortriptyline2D6 substrate
dextromethorphan2D6 substrate
propafenone2D6 substrate/inhibitor
metronidazole
Fluconazole
3A4/2C9 inhibitor
BID 2C9 inhibitor, 3A4 inhibitor
memorize

 

Question Answer
fluvoxamine3A4/1A2/2C9/2C19 inhibitor
omeprazole3A4 substrate, 2C19 inhibitor
rabeprazole3A4 substrate
St. John's wortBIG 3A4/1A2/2C9 inducer
mirtazapine3A4/1A2/2D6 substrate
ciprofloxacin1A2 inhibitor
haloperidol3A4 substrate/inhibitor, 2D6 substrate
telithromycinBIG 3A4 inhibitor
amitriptyline1A2/2D6 substrate
primidone3A4/1A2/2C9 inducer
memorize

 

Question Answer
profofol3A4 inhibitor
modafanil3A4 substrate, 2C19 inhibitor
zafirlukast2C9 inhibitor
sertraline3A4/2D6 inhibitor
donepazil2D6 substrate
escitalopram3A4 substrate
dutasteride3A4 substrate
erithromycin3A4 substrate/BIG inhibitor, 1A2 inhibitor
quinidine3A4 substrate/inhibitor, 2D6 inhibitor
fluconazoleBIG 3A4/2C9 inhibitor
memorize

 

Question Answer
gemfibrozil1A2/2C8 inhibitor
lovastatin3A4 substrate
zolpidem3A4 substrate
nifedipine3A4 substrate
aripiprazole3A4/2D6 substrate
trimethoprim/sulfamethoxazole2C9 inhibitor
levonorgestrel3A4 substrate
apomorphine3A4 substrate
buspirone3A4 substrate
tramadol3A4/2D6 substrate
memorize

 

Question Answer
methamphetamine2D6 substrate
thioridazine2C19/2D6 substrate
aprepitant3A4 substrate/inhibitor, 2C9 inducer
rivaroxaban3A4 substrate
simvastatin3A4 substrate
clarithromycin3A4 substrate, BIG 3A4/1A2 inhibitor
ondansetron3A4 substrate
pioglitazone2C8 substrate
rifampinBIG 3A4/1A2/2C8/2C9/2C19 inducer
amiodarone3A4/2C8 substrate, BIG 3A4/2C9/2D6 inhibitor
memorize

 

Question Answer
grapefruit juiceBIG 3A4 inhibitor
amlodipine3A4 substrate
fluoxetine2C19/2D6 inhibitor
paroxetine2D6 inhibitor
darifenacin2D6 inhibitor
dronedarone3A4 substrate/BIG inhibitor
ropinirole1A2 substrate
lidocaine3A4 substrate/inhibitor, 2D6 substrate
trazodone3A4/2D6 substrate
carbamazepine3A4 substrate, BIG 3A4/1A2/2C8/2C9/2C19 inducer
memorize

 

Question Answer
hydrocodone3A4/2D6 substrate
saquinavir3A4 substrate/BIG inhibitor
felbamate3A4 substrate
indinavir3A4 substrate/BIG inhibitor
duloxetine1A2 substrate, 2D6 inhibitor
buprenorphine3A4 substrate
isoniazid3A4/1A2/2C9 inhibitor
repaglinide3A4/2C8 substrate
clozapine1A2/2D6 substrate
theophylline1A2 substrate
memorize

 

Question Answer
alprazolam3A4 substrate
nelfinavir3A4 substrate/BIG inhibitor
atomoxetine2D6 substrate
lopinavir3A4 substrate
esomeprazole3A4 substrate, 2C19 inhibitor
fentanyl3A4/2D6 substrate
zileuton1A2 inhibitor
clopidogrel2C19 substrate
posaconazoleBIG 3A4 inhibitor
atazanavir3A4 substrate/BIG 3A4 inhibitor, 2C8 inhibitor
memorize

 

Question Answer
eperenone3A4 substrate
oxcarbazepineBIG 3A4 inducer
losartan3A4 substrate
warfarin2C9 inhibitor
nefazodone3A4 inhibitor
apixaban3A4 substrate
smokingBIG 3A4/1A2 inducer
S-warfarin2C9 substrate
vardenafil3A4 substrate
tipranavir3A4 substrate
memorize

 

Question Answer
alosetron1A2 substrate
tadalafil3A4 substrate
ramelteon2C9 substrate
dapsone3A4 substrate
sirolimus3A4 substrate
sildenafil3A4 substrate
nevirapine3A4 substrate/inhibitor
oxycodone3A4/2D6 substrate
olanzapine1A2 substrate
fosamprenavir3A4 substrate/BIG inhibitor
memorize

 

Question Answer
propranolol1A2/2D6 substrate
doxepin2D6 substrate
topiramate2C19 inhibitor
amprenavir3A4 substrate/inhibitor
ranolazine3A4 substrate/inhibitor
estrogens3A4 substrate, 1A2 inducer
celecoxib2C9 substrate
diazepam2C9 substrate
verapamil3A4 substrate/BIG inhibitor
rifapentineBIG 3A4/2C9 inducer
memorize

 

Question Answer
alfentanil3A4 substrate
progesterone3A4 substrate
propoxyphene3A4/2D6 substrate
cimetidineBIG 3A4/1A2/2C9/2C19/2D6 inhibitor
phenytoin2C9/2C19 substrate/inducer, BIG 3A4/1A2/2C8 inducer
rifabutinBIG 3A4 inducer
atorvastatin3A4 substrate
meperidine2D6 substrate
etravirine2C19 inhibitor
alfuzosin 3A4 substrate
memorize

 

Question Answer
carvedilol2C9/2D6 substrate
ketoconazole3A4 substrate/BIG inhibitor, 1A2/2C9/2C19 inhibitor
citalopram3A4 substrate
R-warfarin3A4/1A2 substrate
lansoprazole3A4 substrate
flecainide2D6 substrate
delavirdine3A4 substrate/inhibitor
codeine2D6 substrate
phenobarbitalBIG 3A4/1A2/2C8/2C9/2C19 inducer
cyclosporineBIG 3A4 inhibitor
memorize

 

Question Answer
itraconazoleBIG 3A4 inhibitor
estradiol1A2 substrate
rosiglitazone2C8 substrate
ritonavir3A4 substrate/BIG inhibitor, 2C8/2D6 inhibitor, 1A2 inducer
efavirenz3A4 substrate/inhibitor, 2C19 inhibitor
nateglinide3A4 substrate
desipramine2D6 substrate
methadone1A2/2D6 substrate
rasagiline1A2 substrate
imipramine2D6 substrate
cyclobenzaprine1A2 substrate
memorize