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CVD & CVD studies 2

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bethdrysdale94's version from 2017-01-21 17:40

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Question Answer
Mozaffarian et al (2008) whole study risk factors and outcomesobesity HBP dyslipidemia diabetes and smoking; poor diet, smoking and no PA - increased risk of adiposity, endothelial dysfunction and metabolic dysfunction
Frayn (2010) lipoproteinschylomicrons & VLDL = triglyceride transport. LDL & HDL = cholesterol transport
Simons (1986) whole study cholesterol, HDL and CHDlinear positive association between serum cholesterol and CHD. linear negative association between serum HDL and CHD
Laporte et al (1983) whole study marathon runners and quadriplegicsrunners have high HDL levels (65mg/dl) spinal cord injuries have low HDL (26mg/dl). increase in activity, increase in HDL
STRRIDE study - slentz et al (2005) study infoStudies of Targeted Risk Reduction Interventions through Defined Exercise. exercise intervention (6months) for sedentary people. measured lipoproteins
STRRIDE slentz et al (2005) study findingsexercise reduced VLDL and increased HDL in all exercise interventions. exercise promotes change in lipid profiles; most change in HDL (increase) and triglyceride (decrease). less consistent with total cholesterol and LDL.
STRRIDE slentz et al (2005) study strengths and weaknessescould only be an acute reponse post exercise as measurements were taken only 24hrs post exercise. 2weeks later the changes to lipid profile attenuated.
Kramsch et al (1981) monkeys and diet study info2yr follow up on monkeys, diet and activity: sedentary and normal diet - sedentary and atherogenic diet - exercise and atherogenic diet.
Kramsch et al (1981) study findingsatherogenic fed monkeys; sedentary = major atherosclerosis. exercise = less atherosclerosis but still some increase
Kramsch et al (1981) study weaknessesMONKEYS. how do you really control exercise? not humans
Truswell et al (1972) londoners vs King Bushman studylooked into BP in londoners and king bushman (bushman not westernised and live a far more active lifestyle).
Truswell et al (1972) study findingsLondoners = increase in BP with age. King Bushman had far less increase in BP with age
Truswell et al (1972) study strengths and weaknessesObservational evidence. really representative?
Havard Alumni Health Study (1983) men engaging in sports whole studymen engaging in no sports are 35% more likely to develop hypertension during 6-10yr follow up
Kokkinos et al (1996) African american BP exercise study info46 african american men (predisposed), 50% exercise intervention, 50% no exercise. BP measured at 16&32 weeks
Kokkinos et al (1996) study findingsexercise caused significant decrease in DBP evident at 16&32 week measurements
Kokkinos et al (1996) study strengths and weaknessessmall sample size. one ethnicity, no diversity
Miyashita et al (2008) exercise studynormotensive males, accumulated (10x3min walks) and continuous (1x30 walk) exercises. blood pressure measured the day after. BP decrease only seen the day after exercise.
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