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CV Drugs

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oeshnoeugo123's version from 2018-03-27 05:11

Section

Question Answer
clonidinealpha-2 receptor agonist that acts centrally and is used in the treatment of hypertension
prazosinselective alpha-1 receptor blocker useful in the treatment of hypertension due to its vasodilatory actions
spironolactone (Aldactone)a potassium-sparing diuretic acting in the distal tubule that is a competitive antagonist of aldosterone
clonodinealpha receptor agonist that acts at alpha2 receptors in the CNS to produce vasodilation and is used in the treatment of hypertension; also as adjunct in opioid or alcohol withdrawal treatments
methyldopaalpha receptor agonist that forms false neurotransmitter that acts at alpha2 receptors in the CNS to produce vasodilation
amiodarone (Cordarone)
-Class 3 antiarrhythmic
-K+ channel blocker
-2D6I
Class III antiarrythmic agent used for life threatening arrythmias; turns people blue
clopidogrel (plavix)antiplatelet agent that acts by blocking ADP receptors
heparin
-intrinsic pathway
anticoagulant agent that acts by blocking the conversion of thrombin to prothrombin; effect is measured by PTT
enoxaparin (lovenox)injectable LMWH anticoagulant
aspirinanticoagulant agent which acts by blocking platelet aggregation; effects measured by bleeding time rather than PT time
warfarin (coumadin)anticoagulant that acts by inhibiting synthesis of vitamin-K dependent coagulation factors
dabigatran (pradaxa)
-NOAC
-direct thrombin 2a inhibitor
anticoagulant that is a direct thrombin inhibitor
ranoxaline (ranexa)for chronic angina, inhibits late inward sodium current
Rosuvastatin (Crestor)most potent statin drug
carvedilolantihypertensive agent that blocks both alpha and beta receptors to produce vasodilation
lisinopril (Zestril)
-ACEI
"-pril"
blocks conversion of angiotensin I to angiotension II and thus produces vasodilation to reduce hypertension and congestive heart failure
verapamil
type 1 CCB
class 4 antiarrhythmic
calcium channel blocker used for hypertension and angina but also as a Class IV antiarrythmic agent used to treat supraventricular tachycardia
sacubitrilneprilisyn inhibitor, prevents breakdown of vasodilator peptides like bradykinin, combined with valsartan
-more peptides = vasodilation
nifedipine
-type 2 CCB
-class 4 antiarrhythmic
calcium channel blocker used for hypertension and angina that causes the most gingival hyperplasia
amlodipine (Norvasc)
-type 2 CCB
-class 4 antiarrhythmic
calcium channel blocker used for hypertension and angina that causes the least gingival hyperplasia
rivoroxaban (xarelto)
-NOAC
-factor Xa inhibitor
"-ban"
factor Xa inhibitor anticoagulant
atenolol,
metoprolol
cardioselective beta-1 adrenergic receptor blocker used to treat hypertension
HCTZdiuretic used to treat hypertension that acts in cortical segment of the loop and distal tubule; also has weak vasodilatory action.
nitroglycerindrug of choice for treating angina acutely – reduces preload
furosemide (lasix)high efficiency loop acting diuretic; causes hypokalemia
rosuvastatin (crestor)lipid-lowering agent that is a competitive inhibitor of HMG CoA reductase and acts by inhibiting lipid synthesis
propanololnon-selective beta-blocker used to treat hypertension, angina (chronically), and speakers anxiety; masks hypoglycemia symptoms
quinidine
-for atrial fibrillation
-class 1A antiarrhthmic
Class 1A-antiarrythmic agent that acts by blocking sodium channels
digoxin
-often in combo with a loop diuretic furosemide (lasix)
s47/116
historical drug of choice in the treatment of congestive heart failure
atenolol (tenormin)selective beta-1 blocker used to treat hypertension that is relatively free of CNS related side effects
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Section

Question Answer
prazosinalpha-1 selective BLOCKER
clonidinealpha-2 agonist - selective agonist stimulates alpha-2 receptors in the CNS to reduce sympathetic outflow to peripheral vessels resulting in vasoDILATION
propanololnon-specific beta-1, beta-2 blocker
1. atenolol
2. metoprolol
beta-1 specific blocker
1. Carvedilol
2. Labetolol (Normodyne)
alpha-1 block AND
non specific beta block
1. enalapril (Vasotec)
2. Lisinopril (Zestril)
ACEIs
1. Valsartan (Diovan)
2. Losartan (Cozaar)
ARBs
1. Verapamil
2. diltiazem
Type 1 CCBs
1. Nifedipine (Procardia)
2. Amlodipine (Norvasc)
Type 2 CCBs
hydrochlorothiazide (HCTZ)Thiazide diuretic
furosemide (Lasix)High-ceiling or loop acting diuretic
1. spironolactone
2. amiloride
Potassium sparing diuretic
aliskiren (Tekturna)direct renin inhibitor
Teklamo = aliskiren (Tekturna) + Amlodipine (Norvasc)Combination ANTI hypertensive
-Teklamo
propanolol
Class 2 - beta-blocker
s11/33
used to reduce incidence of ARRHYTHMIAS after MI
amiodarone
class 3 - potassium channel blocker
blue skin discoloration
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Herbals

Question Answer
feverfewherbal(s)
-cause oral ulcers
1. feverfew
2. gingko
-also ginger, garlic, ginseng
herbal(s)
-increase gingival BLEEDING
St John's wortherbal(s)
-cause xerostomia
kavaherbal(s)
-can cause oral & lingual dyskinesia
-dyskinesia = impairment of VOLUNTARY movement
Echinaceaherbal(s)
-can cause tongue numbness
-possibly producing taste changes
garlicherbal(s)
-decreases platelet aggregation more than aspirin
-used to lower serum lipid & cholesterol
gingerherbal(s)
-relieve severity of nausea & vomitting of PREGNANCY
and also...
POST-OPERATIVE + SEASICKNESS
-inhibits thromboxane synthetase
-may prolong bleeding time
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