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Collagen and Diseases

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imissyou419's version from 2016-10-13 17:38

Section

Question Answer
def homotrimericsame gene -> same 3 proteins
def heterotrimericdifferent gene -> similiar 3 proteins
structure of collagen G-X-Y (glycine-proline-hydroxyproline/hydroxylysine) linked w/ water
brittle bone dieasetype 1 collagen mutation of glycine substitution impairing secretion
scurvyno hydroxyation so breakdown
arthritiscollagen destroyed around cartilage connective tissue (type 2)
sarcomatumour of nonepithelial/connective tissue
memorize

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