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CNS & Behavior Modifying Agents - Pharmacology Exam 1

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ewright2's version from 2016-09-06 15:08

Section

Question Answer
Diazepam •Benzodiazepine •Sedative/anxiolytic – used for fear related phobias
Clomipramine•Tricyclic Antidepressants, helps with fears and phobias of animals • Blocks the uptake of serotonin (SERT antagonist) and Norepinephrine (NET antagonist)
Fluoxetine•Helps with compulsive behaviors and dominance-motivated aggression • Selective serotonin reuptake inhibitor • Less sedation than benzodiazepines
Acepromazine •Behavioral quieting, but no specific anxiolytic effect •Not good for long term treatment •Targets D2 receptor – dopamine antagonist
Ketamine•Anesthesia •Noncompetitive antagonists of NMDA receptor
Phencyclidine •NMDA receptor similar to ketamine •Hallucinatory effects
Strychnine•Convulsant •Competitive glycine antagonist
Tetanus ToxinInterferes with glycine release
Botulinum ToxinInhibits ACh release, inhibiting cholinergic tranmission
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