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Clostridium Perfringens

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geferaye's version from 2016-11-02 18:41

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Question Answer
What are the diseases caused?Gas Gangrene (myonecrosis-involves lipoproteins), food poisoning
What are the characteristics?anaerobic, gram-positive, spore forming rod
How is it transmitted?found in soil and human colon, gas gangrene from contaminationof wound with soil or feces, food poisoning by ingestion of contaminated food
What is the pathogenesis? gas gangrene: germination of spores under anaerobic conditions, production of alpha toxin; food poisoning: colonization of GI tract and production of enterotoxin
How can it be diagnosed?gram-stain smear plus anaerobic culture, biochemical tests
How is it treated?tissue debridement plus antibiotics (penicillin). No vaccine
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