Chapter 21 The immune system

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Section 1

Question Answer
1) Saliva and lacrimal fluids contain this enzyme that destroys bacteria. A) Trypsin B) Reverse transcriptase C) Interferon D) LysozymeD) Lysosomes
2) Which of the following statements is not true of natural killer cells? A)They are specialized lymphocytes. B) They are part of the innate defense system. C)They react against very specific pathogens. D)They promote apoptosis.C
3) Neutrophils are able to squeeze through the capillary walls in a process called ________. A) leukocytosis B) margination C) diapedesis D) hyperemiaC
4) During the inflammation process the mast cells release _________, which causes vasodilation. A) Interferon B) histamine C) defensin D) heparin E) endothelinB
5) Which of the following is NOT one of the cardinal signs of inflammation? A) Opsonization B) Heat C)Pain D) Redness E)SwellingA
6) Complement proteins and antibodies coat a microorganism and provide binding sites, enabling macrophages and neutrophils to phagocytize the organism. This phenomenon is termed ________. A) Diapedesis B) Chemotaxis C) Opsonization D)AgglutinationC
7) The basic mechanism employed by complement to fight bacterial infections is _______. A) antibody production B) fever elevation C) bacterial cell membrane lysis D) antiviral protein synthesisC
8) These proteins are released by virus-infected cells and help protect surrounding uninfected cells. A) Complement B)Defensins C) Interferons D) ProstaglandinsC
9) Release of pyrogens directly results in: A) Inflammation B) Fever C) Migration of WBCs D) Cell apoptosis E) B cell activationB

Section 2

Question Answer
10) A "nonself" substance that can provoke an immune response is called a(n) __________. A) Antibody B) Immunoglobulin C) Interferon D) Interleukin E) AntigenE
11) The unresponsiveness of our lymphocytes to our own body cells is called _______. A) immunocompetence B) histocompatibility C) self-tolerance D) immunological memoryC
12) The adaptive immune system involves three major cell types: antigen-presenting cells; T cells, which constitute _______ immunity; and B cells, which govern _______ immunity. A) nonspecific; specific B) antigenic; allergic C) MHC; MAC D) cell-mediated; humoralD
13) The ability of antibodies to block specific sites on pathogens so that they cannot bind to cell receptors is called _______. A) agglutination B) activation C) neutralization D) precipitationC
14) Clone cells capable of secreting large amounts of antibodies are called ______. A) memory cells B) T cells C) plasma cells D) macrophagesC
15) Which of the following best describes an antibody's mode of action? A) Antibodies punch holes in bacterial cell membranes. B) Antibodies immobilize antigens and mark them for destruction. C) Antibodies bind to antigens and transport them to the liver for excretion. D) Antibodies secrete antiviral proteins.B
16) The part of the antibody that binds specifically to an antigen includes: A) The variable regions of the heavy and light chains B) The constant regions of the heavy and light chains C) The variable region of the light chain only D) The constant region of the heavy chain only E) More than one of the aboveA
17) Antibodies are grouped into 5 classes, based on the structure of the ________. A) variable region B) constant region C) heavy chain D) light chainB
18) Which class of immunoglobulin is the most effective at agglutination?Igm
19) A vaccination works to establish __________ immunity. A) Passive naturally-acquired B) Active naturally-acquired C) Passive artificially -acquired D) Active artificially-acquiredD
20) What type of immunity is established after you come down with the flu? (same choices as above)Active Naturally Acquired

Section 3

Question Answer
21) True or false: Like B cells, T cells recognize and bind to free floating antigens. False
22) Which of the following would not be a target of T cell-mediated immunity? A) intracellular pathogens that reside within host cells B) some cancer cells C) foreign tissue transplants D) pathogens in the lumen of the stomachD
23. Most CD4 cells can turn into all the of following EXCEPT: A) Helper T cells B) Regulatory T cells C) Cytotoxic T cells D) Memory T cellsC
24) CD8 cells, when activated, are able to: A) Secrete antibodies B) Directly kill target cells C) Differentiate into Helper T cells D) Release histamine E) All of theseB
25) MHC Class I proteins are found on the plasma membranes of: A) Most body cells B) APCs only C) Most T cells D) Most B cellsA
26) Cytotoxic T cells recognize ______ on ______ cells. A) MHC I; antigen-presenting B)MHC I; all body C) MHC II; antigen-presenting D) MHC II; all body E) All of theseB
27) MHC Class II proteins carrying non-self antigens are recognized by and trigger the activation of:
A) Natural killer cells B) B cells C) Plasma cells D) CD4 T cells E) CD8 T cells

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