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CD MARKERS

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medmaestro's version from 2015-11-17 16:14

Section

Type of cellCD markers
Stem cellsCD34,TdT
Pre B& T Cell(precursor lymphoma)TdT
Pan leucocyte markerCD 45 RB
Naïve T cell(Medullary thymocytes)CD45 RA, CD45 RC
Memory T cell(Cortical thymocytes)CD45 RO
Pan Tcell markerCD3
Pan B cell markerCD19
B LymphocytesCD10(calla antigen)CD19 to 23,CD79a
Matured B cell markerCD23
Myeloid seriesAnti MPO
GranulocyteCD45,CD15
MonocyteCD45,CD14
T lymphocyteCD45,CD3
T helper cellsCD45,CD3,CD4
Cytotoxic T cellCD45,CD3
Megakaryocytes/PlateletsCD61,CD41,CD45
Natural Killer cell (NK)CD16,CD56
NK/T cellCD16,CD56,CD3
Plasma CellCD38
Reed Sternberg cell(Hodgkins lymphoma)CD15,CD30
EBV receptorCd21
GISTCD117(most specific), CD34
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Primary T cell Associated
Question Answer
Antigen DesignationCellular Distribution
CD1Cortical thymocytes & langharn histocytes
CD3Thymocytes,peripheral cells
CD4Helper subset of peripheral T cells ,single positive medullary thymocytes & CD4/CD8 double positive thymocytes.
CD5T cells and small subsets of B cells
CD8Cytotoxic subset of peripheral T cells, single positive medullary thymocytes,double positive cortical thymocytes & some NK cells.
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Primary B cell associated
Question Answer
Antigen DesignationCellular Distribution
CD 10Marrow pre B cell and germinal centre B cells, also called CALLA
CD19Marrow pre B cells and mature B cells but not plasma cells
CD20Marrow pre B cell after CD19 and mature B cells but not plasma cells.
CD21EBV receptor; present on mature B cells & follicular dendritc cells
CD23Activated mature B cells
CD79aMarrow pre Bcells and mature Bcells
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Primary Monocyte or Macrophage Associated
Question Answer
Antigen DesignationCellular Distribution
CD11CGranulocytes,monocytes and macrophages, also expressed by hairy cell Leukemia
CD13Immature and mature monocytes and granulocytes
CD14Monocytes
CD15granulocytes; also expressed by Reed Sternberg cells &variants in classical Hodgkin lymphoma
CD33Myeloid progimtors and monocytes
CD64Mature myeloid cells
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Primary Stem cell and Progenitor cell associated
Question Answer
Antigen DesignationCellular Distribution
CD34Pluripotent hematopoeitic stem cells and progenitor cells of many lineage
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Activation Markers
Question Answer
CD30Activated B cells,T cells and monocytes,also expressed by Reed Sternberg cells and variants in classical Hodgkins lymphoma
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Present on all Leukocytes
Question Answer
Antigen DesignationCellular Distribution
CD45All leukocytes all known as leukocytic common antigen
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