CC Jan 2016 Febrile seizures

echoecho's version from 2016-03-27 21:58


Question Answer
Febrile seizures is the most frequent type of seizure disorder in children, most commonly occurring in children between ____ _____ and ____ years of age with a peak incidence at about _____ ______? 6 months; 5 ; 18 months
Which gender is slightly more affected that the other?boys slightly more affected than girls
What is the most common risk factor fro the development of a first febrile seizure? height of the temperature (the higher the temperature the greater the likelihood of a febrile seizure)
True or false? Rapidity of temperature rise plays a greater role than the actual temperature as to the likelhood of a febrile seizure?false; rapidity of temperature rise plays a lesser role
Most children have a temperature of at least ____ F (____ C) at the time of the seizure?100.4 F; 38 C
List other risk factors for a first febrile seizure?1) first-degree relative with a hx of a febrile seizure 2) neonatal nursey stay > 28 days 3) development delay 4) attendance at a daycare center
About ___ to ____% of children who experience a febrile seizure will have a recurrence, but < ____% will have 3 or more recurrences?30-40%; 10%
What is a factor at the time of the first febrile seizure which is an important risk factor because these individuals have lower seizure threshold?relatively lower temperature (<38 C)
List 6 other risk factors for recurrences of febrile seizures?1) younger age of onset (<12 months) 2) shorter interval between the onset of fever and the initial seizure 3) epilepsy in the first-degree relative 4) febrile seizure in a first-degree relative 5) frequent febrile illness (daycare attendance) 6) first febrile seizure that is complex
*** The greater the number of risk factors, the higher is the rate of ________?recurrence
Of children who have ____ or more of these risk factors, 76% will have recurrence of the febrile seizure, compared with 4% of those children without risk factors?4
Is there a strong genetic predisposition to febrile seizures?yes
The risk for the development of febrile seizures is about ___% when a sibling also had them, and the risk increases to ____% when both parents also have a hx of febrile seizures?20%; 33%
The concordance rate is about ___ to ____% in monozygotic twins and ___-___% in dizygotic twins?35-69%; 14-20%
What is the most likely mode of inheritance for febrile seizures?polygenic or mulltifactorial mode
The _____ of infection plays a role in the pathogenesis of febrile seizures?type
What infection, caused by human herpesvirus 6, is an important cause of first-time febrile seizures?Roseola infantum
List other important causes of febrile seizures?1) otitis media 2) pharyngitis 3) gastroenteritis (especially due to shigellosis and rotavirus)
What infection leads to a higher incidence of feibrile seizures and of recurrent seizures during the same febrile episode than do infections with adenovirus or parainfluenza?Influenza A infections
Describe a simple febrile seizure?1) a generalized event 2) tonic-clonic movements 3) rolling back of eyeballs 4) lasts for a few seconds to a few minutes 5) has a brief postictal period of drowsiness following it
Simple febrile seizures account for ____ to ___% of all febrile seizures?70-75%
Comment on the characteristics of a complex febrile seizure?1) lasts longer than 15 minutes 2) is focal 3) recurs within 24 hours 4) might have a prolonged period of postictal drowsiness or have associated postictal neurologic abnormalities
*** SUMMARY = What risk factor at the time of the first febrile seizure is an important risk factor for recurrent seizure because these individuals have a lower seizure threshold?relatively lower temperature (<38 C)
*** SUMMARY = In most patients, the _____ of the body temperature plays a more important role in the pathogenesis of a febrile seizure than the ______ of the rise in the temperature?height; rapidity