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Category of Anti-Epileptics

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mckel67's version from 2016-05-11 23:56

Section

Question Answer
EthosuximideT-Type Ca2+ channel blocker
ValproateNa+ Channel blocker and T-type Ca2+ blocker
LamotrigineNa+ channel blocker
pregabalin & gabapentinenhances gaba pre synaptically and block glutamate presynaptically
CarbamazepineNa+ channel blocker
BarbituatesEnhance GABA post synaptically
PhenobarbitalNa+ blocker, block glutamate post synaptically
TiagabineEnhance GABA presynaptically
ZonisamidBlock Na+
TopiramateBlock Na+, enhances GABA post synaptically, and blocks glutamate post synaptically
PhenytoinBlock Na+
Vigabatrinenhance GABA presynpatically
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Question Answer
DOC Tonic clonic seizuresvalproate, carbamazepine and phenytoin
DOC myoclonic seizuresvalproate
Status Epilepticus ladderlorazepam -> phenytoin -> phenobarbital -> general anaesthetic (propofol, etc.)
DOC Absence Seizuresethosuxamide or valproate
Drug induced seizuresdiazepam, lorazepam, phenobarbital
Break through seizuresrectal diazepam
Febrile Convulsionstreated pharmacologically if > 15m with IV or rectal diazepam
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