Cancer Ck

mikenakhla's version from 2016-05-19 21:45



Question Answer
• Granulosa cell tumorsexcessive estrogen
• Sertoli leydig cell tumors?androgens, virilization, hirsutism in girls, enlargement of clitoris in girls
• Plaquelike, itchy skin rash that does not improve with treatment, blood smear (cerebriform nuclei known as “butt cells”),mycosis fungoides/sezary syndrome
• HTLV-1 virusT cell leukemia in adults
• Which type of NHL has the best prognosis?small follicular type. Large diffuse has the worst. Primary tumor may be located in GI tract
• Hyperviscous blood, raynaud phenomenon possible, cold agglutinins, IgM spikewaldenstrom macroglobuinemia
• First step of spinal cord compression by mets to the spine? The what? How do you treat?steroids, then MRI. Treat with radiation. If radiation fails, surgery.
• Polyposis plus CNS tumorsturcot syndrome
• Increased incidence of which cancers in Peutz-Jeghers syndrome?stomach, breast, ovarian. Noncancerous GI polyps part of the disease, but NO INCREASED COLON CANCER RISK
• Painless tumor felt in a kid by a doctor in the abdomenwilms tumor
• Hemangioblastomas in cerebellum, RCC, cysts in liver and kidneyvon Hipple Lindau disease
• Liver angiosarcomas, think of this exposurevinyl chloride
• Immigrants with bladder cancer, think thisschistosomiasis
• Treatment for non small cell lung cancer? Small cell?surgery if within just the lung parenchyma (not involving other lung, pleura, chest wall, other structures). Small cell metastasizes early so surgery isn't an option
• Elevated hemidiaphragm on chest X ray with lung cancer?unilateral diaphragm paralysis due to phrenic nerve involvement
• If nodes are positive with a breast cancer, what do you do?give chemo
• Treatment for metastatic prostate cancer?orchiectomy, leuoprolide (GnRH agonist), flutamide (androgen recepter blocker), and GnRH antagonists (degarelix)
• Watery diarrhea, hypokalemia, and achlorhydria with this pancreatic islet tumorVIPomas
• Most ovarian enlargements of women pre-menopause arebenign. Ultrasound is a good first test to evaluate, especially for postmenopausal women
• Most common type of ovarian cancer? What do you see on histology?serous cystandenocarcinoma. Psammoma bodies
• Which ovarian tumors show up as calcifications on an X ray?Teratomas
• Which ovarian tumors cause virilization and which cause feminization/precocious puberty in young girls?sertoli leydig, granulosa/theca cell.
• Ovarian fibroma causing ascites and right hydrothorax?Meigs syndrome
• Most common types of brain tumors in childrencerebellar astrocytoma (benign pilocytic astrocytoma), medulloblastoma, and then ependymoma
• These cancers account for 75% of all brain metslung, breast, melanoma
• Intracranial calcification in a child?craniopharyngioma
• Treatment for seminomas? How do you diagnose?very radiosensitive. Diagnose with ultrasound
• Who gets nasopharyngeal cancer? What is this associated with?Asians, from asia, and EBV
• Increased calcitonin and thyroid tumorMTC, check for MEN syndrome
• Most common primary tumor of the liver that is benign and generally left alonehemangioma
• Treatment for hepatic adenoma?stop OCPs, surgery if it doesn't regress
• Risk factors for cholangiocarcinoma (liver cancer)?UC, liver flukes (clonorchis) in immigrants
• Most common primary liver malignancy in children?hepatoblastoma, malignant
• Left supraclavircular node enlargmentvirchow node, spread of stomach cancer
• Heart findings with carcinoid syndrome?right sided heart valve damage. Flushing, cramps, diarrhea, etc. only symptomatic when mets to liver. Diagnose with 5-HIAA levels
• ABCDE, one of these characteristics, what do you do?excisional biopsy for melanomas
• What do you do for suspicious skin lesion?Excisional biopsy
• Wilms tumor vs neuroblastoma?neuroblastomas arise from adrenals and calcify. Wilms tumors arise from kidney and rarely calcify, so imaging can distinguish the two.
• Oral hairy leukoplakia isn't cancerous, but is seen in HIV patients and associated withEBV. Oral cancer lesions often begin as leukoplakia or malakoplakia (red patch)
• CD 1 positive cells and Birbeck granules (cytoplasmic inclusion bodies that look like tennis rackets)Langerhans cell histiocytosis
• Lytic, benign lesion in the proximal portion of the humerus in kids/teens. It's benign but can weaken the bone enough to cause pathologic fracture of the humerusunicameral bone cyst
• Unilateral exopthalmos in a baby? Can be bilateral too if inheritedRetinoblastoma. Classically has the white reflex too
• Treatment to stabalize bony metastatic lesions to prevent hypercalcemia and fractures in cancer patients. These patients have mild pain. What if they're having more severe pain?bisphosphantes, radiation if more severe

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