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Bone stone

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ktepps's version from 2016-11-22 22:32

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whats the deal with dexter bulldog calvesDexter cattle are frequently heterozygous for an incompletely dominant gene, when this gene becomes homozygous in an individual, the result is a lethal Dexter Bulldog fetus
know all the oddness of the calves of bulldog calvesthey are fidgets of the cow world and sound cute as fuck
Spider lamb syndrome (SLS) isthe most common and important hereditary chondrodysplasia of sheep
what breeds get SLSSuffolk and Hampshire sheep
what individuals show the genetic issueautosomal recessive dz usually die in utero
what do individuals with SLS showAffected animals have long limbs and neck, vertebral scoliosis and or kyphosis, sternal malformation, and valgus deformities of the forelimbs below the carpus (knock-kneed appearance)
where are SLS radiographic and histologic changes most pronouncedin the elbow (anconeal process/olecranon), sternum, vertebrae and scapula
what do the lesions of SLS look likeregions of bone are characterized by multiple irregular foci of ossification separated by numerous, haphazardly organized cartilage plates (dysplastic physes)
name the hyperstotic dz'sosteopetrosis,
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craniomandibular osteopathy, panosteitis, congenital hyperostosis and the more recently described calvarial hyperostosis of Bullmastiff dogs
Question Answer
Osteopetrosis isthe result of a failure of osteoclasts to resorb bone (remodeling of the primary spongiosa into the secondary spongiosa)
what happens do to the failure of osteoclasts in osteopetrosisprimary spongiosa persists and fills up the metaphyseal and diaphyseal marrow cavity
what do the diaphysis look like in osterpetrosisthey are wider than normal. as a result of an osteoclast associated modeling failure in the cutback zone
what happens to intramembranous ossification in osteopetrosisremains normal!
what is Craniomandibular Osteopathy (Lion Jaw)proliferative disorder resulting in new woven bone formation on the mandible and base of the skull, principally the occipital and temporal bones
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how do dogs effected with Craniomandibular Osteopathy aka Lion Jaw presentmouth pain during chewing or an inability to fully open their jaws, waxing and waning course over several weeks; episodic fever is common
how is Craniomandibular osteopathy histologically characterizedperiosteal and endosteal woven bone undergoing intercurrent formation and resorption +/- suppurative inflammation
Metaphyseal osteopathy (MO) occurs in wholarge or giant breed dogs at 3-8 months of age
Metaphyseal osteopathy (MO) was calledhypertrophic osteodystrophy,
where are lesions of MO seendistal metaphyses of the radius and ulna and the lesion is typically bilaterally symmetric
what interesting about MOit is generally self limiting
who gets MOGerman Shepherds, Boxers, Great Danes, Irish setters, and Weimaraners
describe the radiographic lesions of MOcharacteristic radiolucent zone within the metaphysis, parallel to the physeal plate
describe MO histologicallythe metaphyseal lesions have numerous infractions (individualized to clusters of broken trabeculae), necrosis, absence of osteoblasts, suppurative inflammation, fibrin deposition (osteomyelitis) WITHOUT DIRECT EVIDENCE OF MICROBIAL AGENTS
Retained endochondral cartilage cores lesionsa cone-shaped mass of persistent unmineralized cartilage, the base is located on the ulnar growth plate and the apex projecting into the metaphysis
who get retained endochondral cartilage coresgiant breed dogs in the distal ulnar metaphysis and the distal tibial metaphysis of chickens
is retained endochondral cartilage core a serious issueusually an incidental finding but Large persistent cartilage cores can interfere with elongation of the tibia, potentially leading to an angular limb deformation and/or cranial bowing of the radius with carpal rotation
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what is osterochondrosisas a focal failure of endochondral ossification that is likely multifactorial in cause
what do we think that cause of osterochondrosisevidence suggests that it may be the result of a focal failure of blood supply to the growing cartilage
where do lesions of osterochondrosis manifestthese either the physeal plate or the articularepiphysial (AE) complex (articular joint surface)
osteochondrosis dissecans (OCD) isCartilaginous lesion that form a partial to complete flap that can then possibly mineralizr or ossify and these free fragments than cause pain during articulation and are call joint mice
OCD causes what in horsesbone cyst
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who gets aseptic necrosis of the femoral headyoung toy and mini breed dogs with no history of trauma
what is ANFH called in pplLegg-Calve-Perthe's disease
wtf is aseptic necrosis of the femoral headwhen bone of the capital epiphysis is necrotic- lacunae are empty (lack osteocytes) and the intertrabecular space lacks viable adipose tissue and hematopoietic elements maybe bc of ischemia
spinal dysplasias is characterized in dogs bywedge or trapezoidal-shaped vertebrae known as hemivertebrae
spinal dysplasias is characterized in horses bystenosis of the cervical vertebral canal, that can be either sstatic or dynamic (visulazed via radiographs
in osteochondrosis the cervical facets becomebroad and irregular like pancakes, often impinging upon the spinal nerves exiting from the adjacent lateral vertebral formina (leads to equine wobbler disease
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