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Bone cancer

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tomi1's version from 2017-03-07 23:27

Section 1

Question Answer
benign bone cancer examplesosteoid ostemoa, enchondroma, osteochondroma, fibrous dysplasia
primary malignant bone cancererwig sarcoma, (kids) osteosarcoma (young/old), chondrosarcoma (men>40yrs)
secondary malignant bone cancerbreast,lung,renal,thyroid,bowel
haemopoeitc cancer spreading to bone myeloid (elderly), leukemia (young), lymphoma (all ages)
most common benign lesionosteochondroma-painless bony lesion above kneeb
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Section 2

Question Answer
erwig sarcomafemur/tibia-multiple mets-chemo=10%cure rate
osteosarcomaknee-lung mets-surgey+chemo=40%cure rate
chondrosarcomahip-surgery=75% cure rate
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Section 3

Question Answer
red flags bone painbladder/bowel dysfunction,not responsive analgesia, night sweats and pain, painful bony lesion
bone cancer mimics septic arthritisleukemia
bengin cancer mimics malignantosteoid osteoma - painful bone pain at night (BUT sensitive to NSAIDs)
bone cancer causing SC compression featurescauda equina:weak/numb + bladder/bowel dysfunction
SC compression managementradiotherapy to shrink tumor and preserve SC function
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Section 4

Question Answer
lab tests bone cancerBLOODS: crp/alp/est/cancer markers + URINE:bence jonces for myeloma
imaging bone cancerXR-MRI (more sensitive)
management bone cancerMDT: radiotherapy (renal), chemo, HRT (breast)
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