Board memory 1

sbentley's version from 2016-06-29 16:22

Section 1

Question Answer
Nephritic SyndromesPSGN, Goodpastures, RPGN, IGA nephropathy, Membranoproliferative glomerulonephritis
Cresents IgG/c3RPGN
Cresents linearGoodpasture
PSGN IF/EMGranular; Sub-EPI-thelial, lumpy bumpy
granular IF patternPSGN; diffuse proliferative
granulomatous inflamation, asthma, eosinophilia, p-ancachurg strauss
p-ancaChurg strauss; microscopic polyangitis
hematuria and hemoptysis ina young adult maleGoodpastures
thinning and splitting of the glomerular basement membraneAlport syndrome
Membranoproliferative glomerulonephritis IF/EM"Tram track" basement membrane splitting; granular IF
Nephritic then nephroticMembranoproliferative
Sub-ENDO-thelial humps EM; assoc with HCV/HBVMembranoproliferative
IGA nephropathy IFMesanginal proliferation with IgA/c3 deposits specific

Section 2

Question Answer
Nephrotic syndromesMinimal change, FSGN, Membranous nephropathy, amyloidosis, Nodular glomerular sclerosis
BM spikes with silver stainMembranous GN,
Membranous GN IF/EMgranular/ linear; sub-EPI-thelial spikes and dome
Most common in caucasions assoc with lupis Membranous GN
Most common in blacks, hispanics, HIV, hepatitis, sickle cellFSGN
FSGN EM/IFeffacement of foot process, no IF
Most common in kids, normal glomeruli on H and EMinimal change
Type1 membranoprliferative glomerulonephritisSubendothelial,; HBV and HCV
Type2 membranoprliferative glomerulonephritisC3 nephritic factor
glycosylation of the glomerular BM causing sclerosing of mesangiumkimmel wilson nodules diabetes

Section 3

Question Answer
Hexoamidase ATay sachs
A galactosidaseFabrys
Arylsulfatase AMetochromic Leukodystrophy
B glucosidase (Glucocerebrosidase)Gaucher
SphingomyelinaseNeimann Pick
Accumulates in Tay sachsGM2 Gangloside
Accumulates in FabrysGlobtriacylceramide
Accumulates in Metachromic leukodystrophycerebroside sulfate
Accumulates in KrabbesGalactocerebrosidase
Accumulates in GaucherGlucocerebroside
Accumulates in Neimann PickSphingomylin
Accumulates in FarbersCeramide

Section 4

Question Answer
Tay sachsMental retardation, blindness, muscular weakness, lysosomes with onion skin
FabrysSkin rash and kidney failure, peripheral neuropathy hands and feet(full symptoms only in males- x linked ressesive)
Metachromic leukodystrophyMental retardation, ataxia and dementia in adults; demylenation
GaucherHepatosplenomegaly with erosion of long bones, MR in infants, lipid laden M0= tissue paper
Neimann PickHepatosplenomegaly, MR and death early in life
KrabbeMR, myelin almost absent, peripheral neuropathy, optic atrophy, globoid cells
FarbersHoarseness, dermatitis, skeletal deformation, MR, fatal early in life

Section 5

Question Answer
Gluose-6-phosphataseVon geirke I
a-1,4-GlucosidasePompe II
Amylo-1,6-glucosidase (debranching enzyme)Cori III
Branching enzyme a1,4-a1-6Anderson IV
glycogenp phosphorolaseMcardle V
PhosphofructokinaseHers VI
Von geirkeMassive enlargement of the liver, failure to thrive, Severe hypoglycemia, ketosis, hyperuricemia, hyperlipemia
PompeCardiorespiratory failure- death before 2
CoriMilder version of Von geirkeMassive enlargement of the liver, failure to thrive, Severe hypoglycemia, ketosis, hyperuricemia, hyperlipemia
AndersonProgressive chirosis of the liver to failure and death by 2
McCardleExercise intolerance with painful cramps
HersSimilar to vongeirke but milderMassive enlargement of the liver, failure to thrive, Severe hypoglycemia, ketosis, hyperuricemia, hyperlipemia

Section 6

Question Answer
Eyes postBilaterally over the subocciptal nerves
Middle Ear postBilaterally at superior edge of C1 transverse process
Nose/Sinuses postBilaterally at posterior lateral pillar of C2 & at the transverse process of C2
Tongue/ Tonsils postBilaterally just lateral to spinous process of C2
Thyroid postT2 & T3 lamina bilaterally
Eyes antBilaterally at anterior aspect of surgical neck
Middle ear antBilaterally on superior aspect of clavicle just lateral to rib 1
Nose/ Sinuses antBilaterally on superior aspect of rib 1 costochondral junction & superior aspect of rib 2 ~3.5” lateral of sternum
Tongue/tonsils/pharyx antMultiple Bilaterally at 1ST intercostal space just lateral to manubrium
ThyroidBilaterally at 2nd intercostal space just lateral to sternum
Colon posttriangle area from L3-L5 transverse processes to iliac crest
Appendix postT11 lamina of TP Right
Rectum postLateral aspect of posterior mid-sacrum
Small intestine postT8, T9 & T10 lamina of TP
Prostate postLateral sacral base