tasnimjaisee's version from 2017-12-18 09:02


Question Answer
A co-enzyme or co-factor that is tightly associated with the enzyme is called a?Prosthetic group: difference is degree of association
pre digest proteins during manufacture of baby foodsprotease
glucose to fructoseIsomerase
Fructore is _____ than clucose; so it can be used in smaller amounds in ______ foodsSweeter - Slimming
Apoenzyme + Co-factor/Co-enzyme = ?Holoenzyme
Some enzymes are able to catalyze reaction faster than predicted by diffusion-control limitsCirce effect
Activation energy, ΔG‡ between S and P determines the rate at which?equilibrium is reached
The relationship between the rate of a reaction and the activation energy is?inverse and exponential
A reaction can place spontaneously only if the free energy change ΔG is... (positive/negative)+
A negative ΔG indicates that a reaction can?Take place; not predict rate
Modes of Enzymatic Catalysis: Binding EffectsSubstrate binding - Trasition-state
Modes of Enzymatic Catalysis: Chemical EffectsAcid/base catalysis - Covalent catalysis
Catalysis _____ the transition statestabilizes
Enzyme _____ the transition statedestabilizes
Active site must be similar enough to substrate to ensure ______, but different enough to promote ______specificity - change
Stable compounds whose structures resemble unstable transition statesTSAs
Antibodies generated against a TSAAbzymes
[S] < Kmhigh sensitive little activity
cofactorcoenzymes and metals
What plots show relationship between [S] and V0?Lineweaver-Burke plots
Lineweaver-Burke plots (Rleationship, reciprocal, Vmax)Relationship of [S] and Vo - Double reciprocal of 1/Vo vs. 1/[S] - Determines Vmax
catalyzes an early step of glycolysisPFK1
[PEP]/[ADP] is high, PFK1 is ____ inhibited/activatedin
glycogen synthase is catabolic or anabolic?ana
glycogen phosphorylase is catabolic or anabolic?cata
In response to hormones released in the fed state (insulin) both enzymes arephosphorylated or not?

section 7

Question Answer
ketose and aldose differenceketose is double O to C and aldose is double O to c to H
Sugars that differ at a single chiral centerEpimers
Six-membered sugar ring is?Pyranose
5-membered sugar ring is?Furan
Cyclization of glucose involves reaction of?Hydroxyl of C5 with aldehyde C1
α- hydroxyl of anomeric carbon is ____ the plane of the sugar, below or above?below
Cyclization of fructose can involve reaction of?C5 with ketone c2
acts on glucosinolate to produce glucose and isothiocyanateMyrosinase
non-reducing sugar has the suffix?“osyl”
reducing sugar has the suffix?ose
linear polymer of glucose residues through α(1-4) bondsaylose
f α(1-4) linked glucose residues with α(1-6) branch points every 24-30 residuesAmylopectin
chemical difference between cellulose and chitinhydroxyl group at C2 with acetylated amino group
e β 1-4 linkages of cellulose and chitin allow formation of?straight chains
Fibrils are formed by?parallel chains that are linked through hydrogen bonds
α 1-4 linkages of starch and glycogen form a? :hollow, helical structure.
Question Answer
Protein component is linked to to a glycosaminoglycanProteoglycans
The protein constituent is the largest component by weightglycoproteins


Question Answer
Proteins anchored to the membrane by glycosylated phosphoinositol (GPI) are always ____ the cell in/out?out
Proteins anchored to the membrane by fatty acyl or prenyl chains are always ____ the cell in/out?in
AA's located mostly outside the membrane?Asp, Glu, Arg, Lys
which AA's are clustered at the interface between the hydrocarbon chain?Trp and Tyr
light-driven proton pump from archaebacteria has seven membrane spanning α-helicesBacteriorhodopsin
iron uptake protein from E.coli is a β-barrel with 22 membrane spanning strandsFepA
protease that cleaves some of these proteins blocking neurotransmission and causing paralysis and deathBotulinic toxin


Question Answer
caused by UV radiation distort local DNA geometry, interfere with DNA replication, and cause incorrect base pairingCyclobutane thymine dimers and 6-4 photoproducts