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Block 12 Epilepsy

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klau253's version from 2017-05-28 15:57

Section

Types
Question Answer
Generalisedbilateral clonic tonic
Focalmotor/sensory, retainedloss of consciousness, focal seizure with 2ndary generalisation
general aetiologygenetic, hippocampal sclerosis, post trauma, tumors, malformation of cortical development, vascular malform, cerebrovascular disease
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Genetics
Question Answer
Mendelianauto dom nocturnal frontal lobe epilepsy
non-mendelianchildhood absence, juvenile myoclonic
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Question Answer
Epileptic seizurebrief, stereotypical, multiple attacks, non-situational
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Locations of brain and associated functions
Question Answer
Frontal lobeintellectual function, inhibition, bladder continence, saccadic eye movement, motor fxn, expression of language
parietal lobesensory, receptive language (seizure in this area with shorest duration compared to TIA and migraine)
Temporal lobememory, smell, hearing, vestibular, emotion
Temporal lobe epilepsysmell, taste, deja vu, hallucinations, lip smacking, going blank
Occipital lobevision
Occipital seizuresunformed, circular, multicoloured, confined to hemifield
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Single seizure
Question Answer
2 year risk of recurrence40%
Treatment howeverdoes not improve long term outcome
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Treatment
Question Answer
Idiopathic generalised epilepsyNa+ valporate, lamotrigine
Partial seizurecarbamazepien, Na+ valporate, gabapentin
Na+ valporateincrease levels of GABA
carbamazepineNa+ channel inhibitor
phenytoinNa+ channel inhibitor
Gabapentinanalogue of GABA
lamotrigineNa+ channel inhibitor
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