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Bipolar

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munsele's version from 2016-07-02 22:34

Section

Question Answer
First line for manic stateVPA or lithium plus AP
First line for bipolar depressionLithium or lamotrigine
Med of choice in PGLurasidone Cat B
Bipolar 1 vs Bipolar 2Bipolar 1 is more severe, psychosis can be present, can require hospitalization. Key diagnostic symptom is mania
Which Bipolar is more common in females2
Monitoring for LithiumThyroid hormones
Depakote SEalopecia, wt gain, thromocytopenia, tremor, GI upset
Contributing factors to lithium toxicityDecreased salt intake, poor renal fxn
Lithium toxicity >2.5mEqCNS depression, arrhythmia, sz, brain damage, coma
Lithium toxicity >1.5coarse hand tremor, vomiting, persistent diarrhea, confusion, ataxia
VPA organ effectshepatotoxicity, pancreatitis
Lithium and salt relationshipInverse
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