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Biochemistry Enzymes

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Updated 2007-03-01 08:01

Summary

Memorize Biochemistry Enzymes facts.

Enzyme Roles

EnzymeFunction
GalactokinaseGalactose --> Galactose-1-phosphate
Galactose-1-phosphate uridyltransferaseGalactose-1-phosphate --> Glucose-1-phosphate
Hexokinase/glucokinaseGlucose -->Glucose-6-phosphate
Glucose-6-phosphataseGlucose-6-phosphate --> Glucose
Glucose-6-phosphate dehydrogenase (G6PD)Glucose-6-phosphate --> 6-phosphogluconlactone
TransketolaseRibulose-5-phosphate --> Fructose-6-phosphate
PhosphofructokinaseFructose-6-phosphate --> Fructose-1,6-bisphosphate
Fructose-1,6-bisphosphataseFructose-1,6-bisphosphate -->Fructose-6-phosphate
FructokinaseFructose --> F1P
Aldolase BF1 --> DHAP
Pyruvate kinasePhosphoenolpyruvate --> Pyruvate
Pyruvate dehydrogenasePyruvate --> Acetyl Co-A
HMG-CoA reductaseHMG-CoA --> Mevalonate
Pyruvate carboxylasePyruvate --> Oxaloacetate
PEP carboxykinaseOxaloacetate --> Phosphoenolpyruvate
Citrate synthaseOxaloacetate --> Citrate
alpha-ketoglutarate dehydrogenasealpha-ketoglutarate --> Succinyl-CoA
Ornithine transcarbamylaseOrnithine --> Citruline
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Enzyme-Disease Associations

EnzymeAssociations
Galactokinasemild glactosemia
Galactose-1-phosphate uridyltransferasesevere galactosemia
Glucose-6-phosphatasevon Gierke's
Fructokinaseessential fructosuria
Aldolase BFructose intolerance
defective glycolysis or HMP shunthemolytic anemia
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Irreversible enzymes of Gluconeogenesis

EnzymeFunction, location
Pyruvate carboxylasepyruvate --> oxaloacetate, mitochondria
PEP carboxykinaseoxaloacetate --> PEP, cytosol
Fructose-1,6-bisphosphataseFructose-1,6-bisphosphate --> Fructose-6-P, cytosol
Glucose-6-phosphataseG-6-P --> glucose, cytosol
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Irreversible enzymes of Glycolysis

EnzymeFunction
Hexokinase/glucokinaseGlucose --> G-6-P
Phosphofructokinase (rate limiting step)Fructose-6-Phosphate --> Fructose-1,6,bisphosphate
Pyruvate kinasePEP --> pyruvate
Pyruvate dehydrogenasePyruvate --> Acetyl-CoA
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